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No beta cell desensitisation after a median of 68 months on glibenclamide therapy in patients with KCNJ11-associated permanent neonatal diabetes

D Iafusco, C Bizzarri, F Cadario, R Pesavento… - Diabetologia, 2011 - Springer
Received: 28 April 2011 /Accepted: 18 July 2011 © Springer-Verlag 2011 ... Keywords Chronic
. Durability. Efficacy. Glibenclamide . KCNJ11 gene . Kir6.2 . Mutations . Permanent neonatal
diabetes . Sulfonylurea . Therapy ... Abbreviations DEND Developmental delay, epilepsy ...

Pioglitazone Compared to Glibenclamide on Lipid Profile and Inflammation Markers in Type 2 Diabetic Patients During an Oral Fat Load

G Derosa, AFG Cicero, E Fogari… - … and metabolic research, 2011 - cat.inist.fr
The aim of the study was to evaluate the effect of pioglitazone and glibenclamide on lipid profile
and inflammatory parameters during an oral fat load (OFL). A total of 201 type 2 diabetic patients
on treatment with metformin were enrolled in the study; pioglitazone was titrated till 45 mg/ ...
All 2 versions

Interaction of glibenclamide and metformin at the level of translation in pancreatic β cells

Q Wang, Y Cai, M Van de Casteele… - Journal of …, 2011 - Soc Endocrinology
Sulfonylurea and metformin are used in the treatment of diabetes. Their chronic effects on β cells
are not well known. We have shown that sustained exposure of rat β cells to glibenclamide increased
their protein synthesis activity, while metformin caused an inhibition. The effect of ...
Related articles - All 4 versions

Effects of glimepiride and glibenclamide on carotid atherosclerosis in type 2 diabetic patients

N Katakami, H Kaneto, M Matsuhisa… - Diabetes Research and …, 2011 - Elsevier
Glimepiride, a third-generation SU agent, has lesser insulin secretion action compared with conventional
SUs such as glibenclamide. However, its hypoglycemic action is equivalent to them probably
because it improves insulin sensitivity in subjects with and without diabetes [2], [3] and [4]. ...
Related articles - All 3 versions

Effects of short-term therapy with glibenclamide and repaglinide on incretin hormones and oxidative damage associated with postprandial hyperglycaemia in subjects …

JW Stephens, TB Bodvarsdottir, K Wareham… - Diabetes Research and …, 2011 - Elsevier
A randomized clinical trial was performed recruiting 27 subjects (HbA 1c between 7.5 and
10.5%) free from cardiovascular and renal disease. Glucose, insulin, C-peptide, glucagon-like
peptide-1 (GLP-1), glucose-dependent insulinotropic peptide (GIP), total antioxidant ...

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