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Heightened Induction of Proapoptotic Signals in Response to Endoplasmic Reticulum Stress in Primary Fibroblasts from a Mouse Model of Longevity

AAS Akha, JM Harper, AB Salmon… - Journal of Biological …, 2011 - ASBMB
Previous work from our laboratory has shown that primary fibroblasts from long-lived Snell dwarf
mice display a higher sensitivity to the lethal effects of endoplasmic reticulum (ER) stressors,
such as thapsigargin, than cells from normal mice. Here we show that thapsigargin ...

Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression

[HTML] from hematologylibrary.orgM Franco, P Roswall, E Cortez… - …, 2011 - bloodjournal.hematologylibrary.org
Endothelial cells (ECs) in blood vessels under formation are stabilized by the recruitment of
pericytes, both in normal tissues and during angiogenesis in pathologic situations, including
neoplasia. In the tumor vasculature, besides supporting the functionality of blood flow, ...

NLRC5 deficiency does not influence cytokine induction by virus and bacteria infections

H Kumar, S Pandey, J Zou, Y Kumagai… - The Journal of …, 2011 - Am Assoc Immnol
Nucleotide-binding domain and leucine rich repeat containing gene family receptors (NLRs)
are cytosolic proteins that respond to a variety of pathogen and host components to induce inflammatory
cytokines. NLRC5 is a recently identified member of the NLR family that has been ...
Cited by 6 - Related articles - All 4 versions

Pillars Article: Induction By IL 1 and Interferon-γ: Tissue Distribution, Biochemistry, and Function of a Natural Adherence Molecule (ICAM-1). J. Immunol. 1986. 137: …

ML Dustin, R Rothlein, AK Bhan… - The Journal of …, 2011 - Am Assoc Immnol
The Journal of Immunology 5029 250 INTERCKt.LULAK ADHESION MOLECULE-1 CHARACTERIZATION
servatimi). IFN-tí has no effect at concentrations up to 10 ng/ml. Requirement for protein and
mRNA synthesis. Cyclo- hcximidc, an inhibitor of protein synthesis, and actino- mycln D, ...
Cited by 39 - Related articles - All 3 versions

[HTML] Interferon-α Abrogates Tolerance Induction by Human Tolerogenic Dendritic Cells

[HTML] from plos.orgN Bacher, E Graulich, H Jonuleit, S Grabbe… - PloS one, 2011 - dx.plos.org
IFN-α promoted an enhanced maturation of IL-10 DC as demonstrated by upregulation of the
differentiation marker CD83 as well as costimulatory molecules. IFN-α treatment resulted in an
increased capacity of DC to stimulate T cell activation compared to control tolerogenic ...
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