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Innate immunity: AT-rich DNA trapped in the cytoplasm

M Papatriantafyllou - Nature Reviews Immunology, 2011 - nature.com
Analysis of peripheral blood mononuclear cells (PBMCs) from patients with malaria indicated
a high level of expression of type I IFNs, and the authors investigated what initiates this response
to Plasmodium falciparum infection. Haemozoin is an insoluble crystal — formed from ...

Aspartyl aminopeptidase is imported from the cytoplasm to the vacuole by selective autophagy in Saccharomyces cerevisiae

M Yuga, K Gomi, DJ Klionsky… - Journal of Biological Chemistry, 2011 - ASBMB
Macroautophagy is a catabolic process by which cytosolic components are sequestered by double
membrane vesicles called autophagosomes and sorted to the lysosomes/vacuoles to be
degraded. Saccharomyces cerevisiae has adapted this mechanism for constitutive ...
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Actin behavior in bulk cytoplasm is cell cycle regulated in early vertebrate embryos

CM Field, M Wühr, GA Anderson… - Journal of Cell …, 2011 - jcs.biologists.org
The mechanical properties of cells change as they proceed through the cell cycle, primarily owing
to regulation of actin and myosin II. Most models for cell mechanics focus on actomyosin in the
cortex and ignore possible roles in bulk cytoplasm. We explored cell cycle regulation of ...
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Beyond Stereospecificity: Liquids and Mesoscale Organization of Cytoplasm

[PDF] from princeton.eduAA Hyman… - Developmental Cell, 2011 - Elsevier
As biologists, we are generally interested in the following question: How does complexity arise
from molecular interactions? The structures that we study, such as cells or tissues, are many
orders of magnitude larger than the molecules that make them up. What are the rules by ...

Population genetics of the cytoplasm and the units of selection on mitochondrial DNA in Drosophila melanogaster

DM Rand - Genetica, 2011 - Springer
Abstract Biological variation exists across a nested set of hierarchical levels from nucleotides
within genes to pop- ulations within species to lineages within the tree of life. How selection acts
across this hierarchy is a long-standing question in evolutionary biology. Recent studies ...
Related articles - All 2 versions

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