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Tryptamine Derivatives as Novel Non-Nucleosidic Inhibitors Against Hepatitis B Virus

SJ Qu, GF Wang, WH Duan, SY Yao… - Bioorganic & Medicinal …, 2011 - Elsevier
... Tryptamine hydrochloride or 5 substituted tryptamine hydrochlorides (1a d), as started material,
were commercially available. Neutralization of the hydrochlorides with sodium methoxide
in dry methanol afforded the corresponding free primary amines. ...
All 2 versions

The Pictet–Spengler Reaction in Nature and in Organic Chemistry

J Stöckigt, AP Antonchick, F Wu… - Angewandte Chemie …, 2011 - Wiley Online Library
... modification of this region. Feeding the transgenic roots that express the cDNA of a
non-natural STR mutant with 5-substituted tryptamine analogues resulted in the
production of a variety of substituted alkaloid types (Scheme 8).58. ...

Analogs of 5-(substituted benzylidene) hydantoin as inhibitors of tyrosinase and melanin formation

YM Ha, JA Kim, YJ Park, D Park, JM Kim… - … et Biophysica Acta (BBA …, 2011 - Elsevier
... J. Med. Chem. 27 (1992) 61-66. [34] GP Moloney, AD Robertson, GR Martin, S. MacLennan,
N. Mathews, S. Dosworth, A novel series of 2,5-substituted tryptamine derivatives as vascular
5HT1B/1D receptor antagonists, J. Med. Chem. 40 (1997) 2347-2362. ...
All 2 versions

DFT‐based QSAR and Action Mechanism of Phenylalkylamine and Tryptamine Hallucinogens

S Zhang, Y Fan, Z Shi… - Chinese Journal of …, 2011 - Wiley Online Library
... DFT-based QSAR and Action Mechanism of Phenylalkylamine and Tryptamine Hallucinogens ...
1 and 2 is the introduc- tion of lg B, which is a good descriptor for the shape of molecule and
usually is related to the size or polariza- bility of substituted group.14 From Table 3, it can ...
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Diastereoselective cascade reactions toward substituted diazaindeno [2, 1-[alpha]] phenanthrenes

X Wu, H Fang, Q Liu, L Nie, J Chen, W Cao… - Tetrahedron, 2011 - Elsevier
... the scope of this method was examined under the optimal reaction condition (Table 1, entry 2).
A series of α,β-unsaturated aldehydes 4 with different substituents together with 3a and tryptamine
7a were employed. As shown in Table 2, both aromatic and aliphatic substituted α,β ...

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