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CCR5-Delta 32 mutation is strongly associated with primary sclerosing cholangitis

AD Clouston, D Duffy, R Eri… - Genes And …, 2011 - espace.library.uq.edu.au
CCR5 plays a key role in the distribution of CD45RO+ T cells and contributes to generation of
a T helper 1 immune response. CCR5-Delta32 is a 32-bp deletion associated with significant
reduction in cell surface expression of the receptor. We investigated the role of CCR5- ...
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Restorative Proctocolectomy and Primary Sclerosing Cholangitis: An Acceptable Pairing?

CP Heise - Diseases of the Colon & Rectum, 2011 - journals.lww.com
In this issue of Diseases of the Colon & Rectum, Mathis et al 4 present the largest reported series
of IPAA for ulcerative colitis in the setting of PSC. Although liver transplant had occurred previously
in 14% of the patients, the median preoperative Model for End-stage Liver Disease ...
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Electrostatic modifications of the human leukocyte antigen DR P9 peptide‐binding pocket in primary sclerosing cholangitis: Back to the future with human leukocyte …

PT Donaldson - Hepatology, 2011 - Wiley Online Library
... range of different diseases including; primary sclerosing cholangitis,1 primary biliary cirrhosis8,
and drug induced liver injury.9,10 In all of these cases the MHC ... Genome-wide association analysis
in primary sclerosing cholangitis. Gastroenterology 2010; 138: 1102 – 1111. ...
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Short-and long-term surgical outcomes in patients undergoing proctocolectomy with ileal pouch-anal anastomosis in the setting of primary sclerosing cholangitis

KL Mathis, LA Benavente-Chenhalls… - Diseases of the …, 2011 - journals.lww.com
Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining
your privacy and will not share your personal information without your express consent. For more
information, please refer to our Privacy Policy. ... Skip Navigation Links Home > Current ...
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Three ulcerative colitis susceptibility loci are associated with primary sclerosing cholangitis and indicate a role for IL2, REL, and CARD9

M Janse, LE Lamberts, L Franke… - …, 2011 - Wiley Online Library
Our aim was to further clarify the genetic background of PSC. Because of the clinical overlap
between UC and PSC, we first investigated the association of 13 recently identified UC susceptibility
loci in a cohort of 1,186 PSC patients and 1,748 healthy controls. We further analyzed ...
Cited by 4 - Related articles - All 3 versions

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