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High resolution structures of highly bulged viral epitopes bound to the major histocompatibility class I: implications for T-cell receptor engagement and T-cell …

FE Tynan, NA Borg, JJ Miles… - The journal of …, 2011 - espace.library.uq.edu.au
Although HLA class I alleles can bind epitopes up to 14 amino acids in length, little is known
about the immunogenicity or the responding T-cell repertoire against such determinants.
Here, we describe an HLA-B*3508-restricted cytotoxic T lymphocyte response to a ...
Cited by 6 - Related articles - Cached - All 4 versions

Major histocompatibility complex heterozygosity enhances reproductive success

M THOß, P Ilmonen, K Musolf… - Molecular Ecology, 2011 - Wiley Online Library
We investigated how heterozygosity at the major histocompatibility complex (MHC) affects fitness
in wild-derived (F2) house mice (Mus musculus musculus). To compare and control for potential
confounding effects from close inbreeding and genome-wide heterozygosity, we used ...
Cited by 1 - Related articles - All 2 versions

HIV-1 Nef Disrupts Intracellular Trafficking of Major Histocompatibility Complex Class I, CD4, CD8, and CD28 by Distinct Pathways That Share Common Elements

JA Leonard, T Filzen, CC Carter… - Journal of …, 2011 - Am Soc Microbiol
The Nef protein is an important HIV virulence factor that promotes the degradation of host proteins
to augment virus production and facilitate immune evasion. The best-characterized targets of
Nef are major histocompatibility complex class I (MHC-I) and CD4, but Nef also has been ...
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A Single T Cell Receptor Bound to Major Histocompatibility Complex Class I and Class II Glycoproteins Reveals Switchable TCR Conformers

L Yin, E Huseby, J Scott-Browne, K Rubtsova… - Immunity, 2011 - Elsevier
Major histocompatibility complex class I (MHCI) and MHCII proteins differ in structure and
sequence. To understand how T cell receptors (TCRs) can use the same set of variable regions
to bind both proteins, we have presented a comparison of a single TCR bound to both ...
Cited by 1 - All 2 versions

… Epstein-Barr virus-encoded BILF1 protein modulates immune recognition of endogenously processed antigen by targeting major histocompatibility complex class I …

[HTML] from nih.govJ Zuo, LL Quinn, J Tamblyn, WA Thomas… - Journal of …, 2011 - Am Soc Microbiol
Despite triggering strong immune responses, Epstein-Barr virus (EBV) has colonized more than
90% of the adult human population. Successful persistence of EBV depends on the establishment
of a balance between host immune responses and viral immune evasion. Here we have ...
Cited by 1 - Related articles - All 7 versions

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