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Genome-wide detection of meiotic DNA double-strand break hotspots using single-stranded DNA.

HG Blitzblau… - Methods in molecular biology (Clifton, NJ), 2011 - Springer
The controlled fragmentation of chromosomes by DNA double-strand breaks (DSBs) initiates
meiotic recombination, which is essential for meiotic chromosome segregation in most
eukaryotes. This chap- ter describes a straightforward microarray-based approach to ...
All 2 versions

Double Strand Break Repair, one mechanism can hide another: Alternative non-homologous end joining.

E Rass, A Grabarz, P Bertrand… - … radiotherapie: journal de …, 2011 - ncbi.nlm.nih.gov
... This mechanism is also initiated by a single strand resection of the break. The aim of this
review is firstly to present recent data on single strand resection, and secondly the alternative
NHEJ pathway, including a discussion on the fidelity of NHEJ. ...

Topoisomerase 1 and Single-Strand Break Repair Modulate Transcription-Induced CAG Repeat Contraction in Human Cells

L Hubert Jr, Y Lin, V Dion… - Molecular and Cellular …, 2011 - Am Soc Microbiol
Expanded trinucleotide repeats are responsible for a number of neurodegenerative
diseases, such as Huntington disease and myotonic dystrophy type 1. The mechanisms that
underlie repeat instability in the germ line and in the somatic tissues of human patients ...
Related articles - All 3 versions

The role of homologous recombination in radiation-induced double-strand break repair

PA Jeggo, V Geuting… - Radiotherapy and Oncology, 2011 - Elsevier
... Keywords: Homologous recombination; Double-strand break repair; Ionizing radiation; G2-phase;
Non-homologous end ... induces a variety of DNA lesions of which DNA double-strand breaks (DSBs ...
genomic instability and cell death [1], [2] and [3]. DNA single-strand breaks (SSBs ...
Related articles - All 3 versions

A novel nonsense mutation in the APTX gene associated with delayed DNA single-strand break removal fails to enhance sensitivity to different genotoxic agents

[PDF] from peerproject.euM Bassi, C Crimella, O Cantoni, A Guidarelli… - 2011 - repository.peerproject.eu
For Peer Review A novel nonsense mutation in the APTX gene associated with delayed DNA
single-strand break removal fails to enhance sensitivity to different genotoxic agents ... Date
Submitted by the Author: 13-Dec-2010 ... Complete List of Authors: Crimella, Claudia; E. ...

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