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An Open Sarcolemmal Adenosine Triphosphate-Sensitive Potassium Channel Is Necessary for Detrimental Myocyte Swelling Secondary to Stress

AD Sellitto, AS Al-Dadah, RB Schuessler… - Circulation, 2011 - Am Heart Assoc
Methods and Results—To investigate the role of the sK ATP channel in stress-induced myocyte
swelling, high-dose pharmacological sK ATP channel blockade and genetic deletion (knockout
of Kir6.2 subunit) were used. Myocytes were exposed sequentially to Tyrode control (20 ...

Crystal structure of a potassium ion transporter, TrkH

Y Cao, X Jin, H Huang, MG Derebe, EJ Levin… - Nature, 2011 - nature.com
The TrkH/TrkG/KtrB proteins mediate K + uptake in bacteria and probably evolved from simple
K + channels by multiple gene duplications or fusions. Here we present the crystal structure of
a TrkH from Vibrio parahaemolyticus. TrkH is a homodimer, and each protomer contains ...
Cited by 7 - Related articles - All 6 versions

On the Structure of Vacancy Ordered Superconducting Potassium Iron Selenide

[PDF] from arxiv.orgP Zavalij, W Bao, XF Wang, JJ Ying… - Arxiv preprint arXiv: …, 2011 - arxiv.org
Single crystal X-ray diffraction shows that superconducting K0.92(8)Fe1.54(1)Se2 has an ordered
vacancy structure with a (5 x 5 x 1) super cell. The tetragonal unit cell, space group I4/mmm,
of a = b = 19.495(3) Å and c = 14.0853(19) Å at 250 K, contains 6 inequivalent Fe ...
Cited by 29 - Related articles - All 2 versions

Non-cardiovascular drugs that inhibit hERG-encoded potassium channels and risk of sudden cardiac death

C van Noord, MCJM Sturkenboom, SMJM Straus… - Heart, 2011 - heart.bmj.com
Methods and results The risk of SCD was studied in the Integrated Primary Care Information
database, a longitudinal general practice research database. A case-control study was
performed, matched for age, gender and calendar time. Odds ratios were calculated with ...
Cited by 2 - Related articles - All 4 versions

Voltage-gated potassium channel KCNV2 (Kv8. 2) contributes to epilepsy susceptibility

[PDF] from vanderbilt.eduBS Jorge, CM Campbell, AR Miller… - Proceedings of the …, 2011 - National Acad Sciences
Mutations in voltage-gated ion channels are responsible for several types of epilepsy. Genetic
epilepsies often exhibit variable severity in individuals with the same mutation, which may be
due to variation in genetic modifiers. The Scn2a Q54 transgenic mouse model has a ...
Cited by 1 - Related articles - All 4 versions

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