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The Dll4/Notch pathway controls postangiogenic blood vessel remodeling and regression by modulating vasoconstriction and blood flow

[HTML] from hematologylibrary.org…, R Wudali, J Cao, G Halasz, Y Wei… - …, 2011 - bloodjournal.hematologylibrary.org
Blood vessel remodeling is crucial to the formation of the definitive vasculature, but little is known
about the mechanisms controlling this process. We show that Delta-like ligand 4 (Dll4)/Notch
pathway regulates vessel regression in normal pathologic conditions. Genetic and ...
Related articles - All 2 versions

MicroRNA regulation of neural plasticity and memory

TW Bredy, Q Lin, W Wei, D Baker-Andresen… - … of Learning and …, 2011 - Elsevier
MicroRNAs (miRNAs) are a class of endogenous, small non-coding RNAs that mediate
post-transcriptional gene silencing by complementary binding to the 3'untranslated region of
target mRNAs. The transient and localized expression of these small RNAs in dendrites, ...
All 2 versions

Mitofusin 2 Regulates STIM1 Migration from the Ca2+ Store to the Plasma Membrane in Cells with Depolarized Mitochondria

K Singaravelu, C Nelson, D Bakowski… - Journal of Biological …, 2011 - ASBMB
Store-operated Ca 2+ channels in the plasma membrane (PM) are activated by the depletion
of Ca 2+ from the endoplasmic reticulum (ER) and constitute a widespread and highly conserved
Ca 2+ influx pathway. After store emptying, the ER Ca 2+ sensor STIM1 forms multimers, ...
Cited by 1 - Related articles - All 3 versions

RIM proteins activate vesicle priming by reversing autoinhibitory homodimerization of Munc13

L Deng, PS Kaeser, W Xu… - Neuron, 2011 - Elsevier
At a synapse, the presynaptic active zone mediates synaptic vesicle exocytosis. RIM
proteins are active zone scaffolding molecules that—among others—mediate vesicle
priming and directly or indirectly interact with most other essential presynaptic proteins. In ...
Cited by 6 - Related articles - All 2 versions

Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling

W Tan, W Zhang, A Strasner, S Grivennikov… - Nature, 2011 - nature.com
Inflammatory mechanisms influence tumorigenesis and metastatic progression even in cancers
whose aetiology does not involve pre-existing inflammation or infection, such as breast and prostate
cancers 1 . For instance, prostate cancer metastasis is associated with the infiltration of ...
Cited by 12 - Related articles - All 4 versions

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