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[HTML] mGlu2 metabotropic glutamate receptors restrain inflammatory pain and mediate the analgesic activity of dual mGlu2/mGlu3 receptor agonists

[HTML] from molecularpain.comM Zammataro, S Chiechio, MC Montana… - Molecular …, 2011 - molecularpain.com
Group II metabotropic glutamate receptors (mGluRs) couple to the inhibitory G-protein Gi. The
group II mGluRs include two subtypes, mGlu2 and mGlu3, and their pharmacological activation
produces analgesic effects in inflammatory and neuropathic pain states. However, the ...
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Central and peripheral sites of action for CB2 receptor mediated analgesic activity in chronic inflammatory and neuropathic pain models in rats

GC Hsieh, M Pai, P Chandran… - British journal of …, 2011 - Wiley Online Library
1 Central and peripheral sites of action for CB2 receptor mediated 1 analgesic activity in chronic
inflammatory and neuropathic pain 2 models in rats* 3 ... tetrahydrocannabinol (THC) retained
analgesic activity in knockout animals 23 lacking the CB1 receptor (Zimmer et al., 1999). ...
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Process for preparing a pharmaceutical composition with anti-inflammatory and analgesic activity for administration via a patch for external use, and composition thus …

A Troiano… - US Patent 7,943,668, 2011 - Google Patents
IIIIIIIH US007943668B2 (12) United States Patent ao) Patent no.: us 7,943,668 B2 Troiano et
al. (45) Date of Patent: May 17,2011 (54) PROCESS FOR PREPARING A PHARMACEUTICAL
COMPOSITION WITH ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY FOR ...
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ChemInform Abstract: Synthesis and Pharmacological Evaluation of Condensed Heterocyclic 6‐Substituted 1, 2, 4‐Triazolo‐[3, 4‐b]‐1, 3, 4‐thiadiazole and 1, 3, 4‐ …

SJ Gilani, SA Khan… - ChemInform, 2011 - Wiley Online Library
... Get PDF (27K). Keywords: pyridine derivatives; ring closure reactions;
antiinflammatory activity; analgesic activity. Abstract. ...

[HTML] Experimental evaluation of antipyretic and analgesic activity of aspartame

[HTML] from nih.govS Pradhan, UH Shah, A Mathur… - Indian Journal of …, 2011 - ncbi.nlm.nih.gov
It has been reported that aspartame is biologically active and appears to relieve pain and induce
mild antithrombotic effects in humans, and decrease fever in animals.[1] There is, however, a
paucity of data about the biological effects of aspartame, which prompted us to undertake ...
Cited by 1 - Related articles - All 4 versions

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