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[CITATION] Atorvastatin and pitavastatin improve cognitive function and reduce senile plaque and phosphorylated tau in aged APP mice

K Abe, T Kurata, K Miyazaki, M Kozuki… - Alzheimer's and …, 2011 - Elsevier

Spherulites in Human Brain Tissue are Composed of Beta Sheets of Amyloid and Resemble Senile Plaques

E House, K Jones… - Journal of Alzheimer's Disease, 2011 - IOS Press
... 7 8 9 10 11 Keywords: Alzheimer's disease, amyloid-ß, Congo red, human brain, senile plaque,
spherulites, thioflavin T 12 ... ACKNOWLEDGMENTS 146 Professor MM Esiri (Radcliffe Hospital,
Oxford) is 147 thanked for assessments of senile plaque densities in 148 each case. ...
All 2 versions

Alpha T-catenin (CTNNA3): a gene in the hand is worth two in the nest

JD Smith, MH Meehan, J Crean… - Cellular and Molecular Life …, 2011 - Springer
... [19] found no association between the same two SNPs and clinical markers of LOAD such
as age-at-onset (AAO), mini-mental state examination (MMSE) scores, CSF Ab42, tau levels,
and senile plaque and neurofibrillary tangle (SP–NFT) scores. ...
Related articles - All 2 versions

Pathological Changes Induced by Amyloid-β in Alzheimer's Disease.

K Takata, Y Kitamura… - Yakugaku zasshi: Journal of …, 2011 - ncbi.nlm.nih.gov
... The pathologic hallmarks of Alzheimer's disease (AD) include senile plaque, neurofibrillary tangles
(NFTs), synaptic loss, and neurodegeneration. Senile plaque and NFTs are formed by
accumulation of amyloid-β (Aβ) and hyperphosphorylated tau, respectively. ...

Insulin receptor mutation results in insulin resistance and hyperinsulinemia but does not exacerbate Alzheimer's-like phenotypes in mice

K Murakami, S Yokoyama, N Murata… - Biochemical and …, 2011 - Elsevier
... The insulin receptor mutation reduced oxidative damage in AD mice. ► Insulin resistance and
hyperinsulinemia is always not involved in AD progression. Keywords: Insulin resistance;
Hyperinsulinemia; Insulin signaling; Alzheimer's disease; amyloid β; Senile plaque. ...
All 2 versions

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