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Factor H-related protein 1 neutralizes anti-factor H autoantibodies in autoimmune hemolytic uremic syndrome

S Strobel, C Abarrategui-Garrido… - Kidney …, 2011 - nature.com
... The autoimmune form of atypical hemolytic uremic syndrome (HUS) is characterized by circulating
autoantibodies against the complement regulator factor H, and is ... erythrocytes caused by patient
plasma containing anti-factor H IgG, but it did not inhibit red cell lysis caused by a ...
All 3 versions

Novel developments in thrombotic microangiopathies: is there a common link between hemolytic uremic syndrome and thrombotic thrombocytic purpura?

PF Zipfel, G Wolf, U John, K Kentouche… - Pediatric Nephrology, 2011 - Springer
... Hemolytic uremic syndrome Hemolytic uremic syndrome (HUS) is a disease that is
associated with thrombocytopenia, microangiopathic hemo- lytic anemia, and with
acute renal failure. This disease, which was initially described ...
Related articles - All 2 versions

The development of atypical hemolytic uremic syndrome depends on complement C5

[HTML] from nih.govEG de Jorge, P Macor… - Journal of the …, 2011 - Am Soc Nephrol
... Complement functions include host protection against pathogens through cell lysis, recruitment
of inflammatory cells, and opsonization ... including age-related macular degeneration, dense deposit
disease, C3 glomerulonephritis, 3 and atypical hemolytic uremic syndrome (aHUS ...
Cited by 4 - Related articles - All 4 versions

Clinical Relevance of Shiga Toxin Concentrations in the Blood of Patients With Hemolytic Uremic Syndrome

M Brigotti, PL Tazzari, E Ravanelli… - The Pediatric …, 2011 - journals.lww.com
... Most cases of hemolytic uremic syndrome (HUS) 1 occur as a complication of intestinal infections ...
Information on hemolytic anemia, platelet and leukocyte counts, serum creatinine concentrations,
dialysis ... 19 Briefly, leukocytes isolated after erythrocyte lysis from 100 μL of blood ...
Cited by 3 - Related articles - All 4 versions

Human neutralizing antibodies against hemolytic uremic syndrome

S Tzipori, R Balakrishnan… - US Patent 7,910,096, 2011 - Google Patents
... Microbiol., 39(5): 1932-7 (2001). Razzaq, "Hemolytic uremic syndrome: an emerging
healthrisk",i4m. Fam. Physician, 74(6):991-6 (2006). Reisbig, "The cytotoxic activity of shigella
toxin, evidence for cata- lytic inactivation of the 60 s ribosomal subunit", J. Biol. ...
Related articles - All 4 versions

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