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The Evolution of Bioinformatics in Toxicology: Advancing Toxicogenomics

CA Afshari, HK Hamadeh… - Toxicological Sciences, 2011 - Soc Toxicology
As one reflects back through the past 50 years of scientific research, a significant accomplishment
was the advance into the genomic era. Basic research scientists have uncovered the genetic
code and the foundation of the most fundamental building blocks for the molecular activity ...
Cited by 1 - Related articles - All 3 versions

In vivo and In vitro Assessment of Particulate Matter Toxicology

US Akhtar, JA Scott, A Chu… - Urban Airborne Particulate Matter, 2011 - Springer
Air pollution is a major threat to human health worldwide. According to a World Health Organization
report (WHO 2006), more than two million premature deaths can be attributed each year to air
pollution. In Canada, premature deaths associated with chronic exposure to air pollution ...
Related articles - All 2 versions

Cell death mechanisms and their implications in toxicology

S Orrenius, P Nicotera… - Toxicological Sciences, 2011 - Soc Toxicology
Necrotic cell death was long regarded as the ultimate consequence of chemical toxicity and was
thought to result from simple cell failure because of toxic interference with vital cell functions.
Introduction of the novel concept of programmed cell death (PCD), or apoptosis, has ...
Cited by 3 - Related articles - All 4 versions

[CITATION] Designer drugs intoxications reported to the Department of Toxicology in Poznan in 2010

K Sommerfeld, M Lukasik-Glebocka… - Toxicology Letters, 2011 - Elsevier

Genetic Polymorphism and Toxicology—With Emphasis on Cytochrome P450

I Johansson… - Toxicological Sciences, 2011 - Soc Toxicology
Individual susceptibility to environmental, chemical, and drug toxicity is to some extent determined
by polymorphism in drug-metabolizing enzymes, in particular the cytochromes P450 (CYPs).
This polymorphism is in particular translated into risk differences concerning drugs ...
Cited by 9 - Related articles - All 4 versions

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