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Dominant TNF-[alpha]+ Mycobacterium tuberculosis-specific CD4+ T cell responses discriminate between latent infection and active disease

[PDF] from chuv.chA Harari, V Rozot, FB Enders, M Perreau… - Nature Medicine, 2011 - nature.com
Rapid diagnosis of active Mycobacterium tuberculosis (Mtb) infection remains a clinical and laboratory
challenge. We have analyzed the cytokine profile (interferon-γ (IFN-γ), tumor necrosis
factor-α (TNF-α) and interleukin-2 (IL-2)) of Mtb-specific T cells by polychromatic flow ...
Cited by 9 - Related articles - All 4 versions

Identification and Sequencing of a Novel Rodent Gammaherpesvirus That Establishes Acute and Latent Infection in Laboratory Mice

J Loh, G Zhao, CA Nelson, P Coder, L Droit… - Journal of …, 2011 - Am Soc Microbiol
Gammaherpesviruses encode numerous immunomodulatory molecules that contribute to their
ability to evade the host immune response and establish persistent, lifelong infections. As the
human gammaherpesviruses are strictly species specific, small animal models of ...
Related articles - All 4 versions

Health-Related Quality Of Life In Active And Latent Tuberculosis Patients, And A Matched Comparison Group

M Bauer, C Greenaway, M Lalli… - American Journal of …, 2011 - Am Thoracic Soc
McGill University and the Montreal Chest Insitute, Montreal, QC, Canada, Sir Mortimer B.
Davis—Jewish General Hospital, Montreal, QC, 1 ... Canada, Montreal Chest Institute,
Montreal, QC, Canada, University of Montreal, Montreal, QC, Canada, 3
All 3 versions

Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection

CB Ford, PL Lin, MR Chase, RR Shah… - Nature Genetics, 2011 - nature.com
Tuberculosis poses a global health emergency, which has been compounded by the emergence
of drug-resistant Mycobacterium tuberculosis (Mtb) strains. We used whole-genome sequencing
to compare the accumulation of mutations in Mtb isolated from cynomolgus macaques ...
Cited by 3 - Related articles - All 5 versions

Latent KSHV infection increases the vascular permeability of human endothelial cells.

C Guilluy, Z Zhang, PM Bhende, L Sharek, L Wang… - Blood, 2011 - ncbi.nlm.nih.gov
Kaposi's sarcoma-associated herpesvirus (KSHV) is associated with three different human malignancies
including Kaposi's sarcoma (KS), primary effusion lymphoma and multicentric Castleman's
disease. The KS lesion is driven by KSHV-infected endothelial cells and is highly ...

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