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Endogenous cortisol and TGF-β in human aqueous humor contribute to ocular immune privilege by regulating dendritic cell function

AK Denniston, SH Kottoor, I Khan… - The Journal of …, 2011 - Am Assoc Immnol
Aqueous humor (AqH) has been shown to have significant immunosuppressive effects on APCs
in animal models. We wanted to establish whether, in humans, AqH can regulate dendritic cell
(DC) function and to identify the dominant mechanism involved. Human AqH inhibited the ...
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[HTML] Alterations in the aqueous humor proteome in patients with a glaucoma shunt device

[HTML] from molvis.orgA Anshu, MO Price, MR Richardson, ZM Segu… - 2011 - molvis.org
Results: We identified 135 proteins in the albumin-depleted fraction in both the study and control
group AH. Using stringent criteria, 13 proteins were detected at a significantly higher level compared
to controls. These proteins are known to play a role in oxidative stress, apoptosis, ...
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Rho GTPase‐mediated cytoskeletal organization in Schlemm's canal cells play a critical role in the regulation of aqueous humor outflow facility

J Kumar, DL Epstein - Journal of cellular biochemistry, 2011 - Wiley Online Library
The increased intraocular pressure (IOP) has been considered to be an increased resistance
of the aqueous humor outflow through the inner wall of Schlemm's canal (SC) and/or the juxtacanalicular
tissue (JCT). The Rho GTPase-regulated actomyosin organization appears to be an ...
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Assumption Constraints of Fluorophotometry in Human Eyes

V Gulati… - Investigative Ophthalmology & Visual Science, 2011 - ARVO
... Introduction. We read with great interest the article entitled “Fluorophotometric Study of the Effect
of the Glaukos Trabecular Microbypass Stent on Aqueous Humor Dynamics” by
Fernández-Barrientos et al. ... Uveoscleral drainage of aqueous humour in human eyes. Exp Eye ...
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Penetration of Topically Administered 0.5-Percent Caspofungin Eye Drops into Human Aqueous Humor

CF Neoh, L Leung, A Misra… - Antimicrobial Agents …, 2011 - Am Soc Microbiol
Caspofungin has activity against a wide range of fungi, with MIC 90 values ranging from 60 to
2,000 ng/ml (15, 23). Caspofungin eye drops are effective for treatment of fungal keratitis in rabbits
(11, 18) and have good penetration into animal eyes with inflammation or previous ...
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