推荐同事 机构合作 中文 繁體中文 English 한국어 日本語 Português Español

美国ACCDON公司旗下品牌

021-33361733，021-33632861

chinasupport@letpub.com

登录 注册 新注册优惠

Calreticulin Inhibits Prion Protein PrP-(23–98) Aggregation in Vitro

N SHIRAISHI, Y INAI, Y HIRANO… - Bioscience, Biotechnology, …, 2011 - J-STAGE
... in cattle, and kuru or Gerstmann– Straussler–Scheinker disease, fatal familial insomnia,
Creutzfeldt–Jakob disease (CJD), and variant CJD in humans, are fatal neurodegenerative
disorders associated with the conversion of PrPC into the infectious scrapie isoform (PrPSc).1 ...

Normal Modes of Prion Proteins: From Native to Infectious particle

AO Samson… - Biochemistry, 2011 - ACS Publications
... disease to structure have also been made through the identification of the minimal prion protein
fragment that is capable of conferring propagation of the scrapie agent Page 4 of 27 ... understood
and structures of the monomeric isoforms and oligomers are still unresolved. ...
Related articles - All 3 versions

Effect of Glycans and the Glycophosphatidylinositol Anchor on Strain Dependent Conformations of Scrapie Prion Protein: Improved Purifications and Infrared Spectra

GS Baron, AG Hughson, GJ Raymond… - Biochemistry, 2011 - ACS Publications
... have made these analyses possible: (1) the recent availability of scrapie-infected transgenic
mice expressing only anchorless PrP molecules that are also severely deficient in Asn-linked
glycans (eg, see the predominance of the lower, unglycosylated isoform in panels A and B ...
Cited by 2 - Related articles - All 2 versions

Glycosylphosphatidylinositol Anchor-Dependent Stimulation Pathway Required for Generation of Baculovirus-Derived Recombinant Scrapie Prion Protein

M Imamura, N Kato, M Yoshioka, H Okada… - Journal of …, 2011 - Am Soc Microbiol
... Chem. 285:14083-14087.[Abstract/Free Full Text]; 20. Kim, JI, K. Surewicz, P. Gambetti, and WK
Surewicz. 2009. The role of glycophosphatidylinositol anchor in the amplification of the scrapie
isoform of prion protein in vitro. FEBS Lett. 583:3671-3675.[CrossRef][Medline]; 21. ...
Related articles - All 4 versions

[HTML] Accumulation and aberrant composition of cholesteryl esters in Scrapie-infected N2a cells and C57BL/6 mouse brains

[HTML] from lipidworld.comS Vascellari, S Banni, C Vacca… - Lipids in health and …, 2011 - lipidworld.com
... Taraboulos A, Scott M, Semenov A, Avrahami D, Laszlo L, Prusiner SB, Avraham D: Cholesterol
depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit
formation of the scrapie isoform. J Cell Biol 1995, 129:121-132. ...
Cached

联系我们 | 站点地图 | 友情链接 | 授权代理商 | 加入我们

© 2010-2024 中国: LetPub上海分公司    网站备案号：沪ICP备10217908号-1    沪公网安备号：31010402006960

增值电信业务经营许可证：沪B2-20211595

礼翰商务信息咨询（上海）有限公司      办公地址：上海市徐汇区漕溪北路88号圣爱大厦1803室

United States: Tel: 1-781-202-9968 Address: 400 5th Ave, Suite 530, Waltham, Massachusetts 02451