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3, 4-Methylenedioxymethamphetamine (MDMA) alters acute gammaherpesvirus burden and limits interleukin 27 responses in a mouse model of viral infection

DA Nelson, SJ Singh, AB Young, MD Tolbert… - Drug and Alcohol …, 2011 - Elsevier
... While this common viral infection is seldom life threatening, the immune status of the individual
influences the severity and length of the acute illness. Furthermore, upon recovering from
mononucleosis, EBV becomes latent and persists for the life of the individual. ...
All 3 versions

Identification and Sequencing of a Novel Rodent Gammaherpesvirus That Establishes Acute and Latent Infection in Laboratory Mice

J Loh, G Zhao, CA Nelson, P Coder, L Droit… - Journal of …, 2011 - Am Soc Microbiol
... To further investigate whether RHVP can establish latent infection in splenocytes, we performed
PCR using primers to RHVP ORF 50 to detect the presence of the viral genome in the same
splenocyte and peritoneal cell samples analyzed in the ex vivo reactivation assays above ...
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KIR and HLA Genotypes in Control of Viral Infection

M Carrington… - Annual Review of Immunology, 2011 - annualreviews.org
... and becomes detectable in plasma (Figure 3). Subsequent rapid viral replication in activated
CD4 T cells and systemic spread lead to an exponential increase in plasma viral load, which
reaches its peak 3–4 weeks after infection (15). By this time, latent viral reservoirs are ...
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[HTML] Global mRNA Degradation during Lytic Gammaherpesvirus Infection Contributes to Establishment of Viral Latency

[HTML] from plos.orgJM Richner, K Clyde, AC Pezda, BYH Cheng… - PLoS pathogens, 2011 - dx.plos.org
... biphasic lifecycle comprised of a lytic replicative stage and a relatively dormant latent stage ... During
a lytic gammaherpesvirus infection, cellular gene expression is severely compromised in a process ...
In this study, we address the purpose of this activity in the viral lifecycle through ...
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4-1BB Signaling Synergizes with Programmed Death Ligand 1 Blockade To Augment CD8 T Cell Responses during Chronic Viral Infection

V Vezys, P Penaloza-MacMaster… - The Journal of …, 2011 - Am Assoc Immnol
... Page 3. with transfer of transgenic virus-specific CD8 T cells, there is a 99% reduction of viral
loads, as well as increased numbers of transferred T cells. ... 4-1BB 2/2 mice have reduced numbers
of memory CD8 T cells during latent murine CMV infection, but paradoxically ...
Related articles - All 2 versions

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