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Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver

[HTML] from pnas.orgCH Österreicher… - Proceedings of the …, 2011 - National Acad Sciences
Cirrhosis is the end result of chronic liver disease. Hepatic stellate cells (HSC) are believed to
be the major source of collagen-producing myofibroblasts in cirrhotic livers. Portal
fibroblasts, bone marrow-derived cells, and epithelial to mesenchymal transition (EMT) ...
Cited by 9 - Related articles - All 5 versions

Liver-specific loss of GRP78 perturbs globally unfolded protein response and exacerbates a spectrum of acute and chronic liver diseases.

C Ji, N Kaplowitz, MY Lau, E Kao… - Hepatology ( …, 2011 - ncbi.nlm.nih.gov
The endoplasmic reticulum (ER) chaperone protein glucose-regulated protein 78
(GRP78/BiP) is a master regulator of ER homeostasis and stress response which are implicated
in pathogenesis of metabolic disorders. By applying the LoxP-Cre strategy, we generated ...

[PDF] Liver-specific deletion of protein tyrosine phosphatase (PTP) 1B improves obesity-and pharmacologically-induced endoplasmic reticulum stress.

[PDF] from biochemj.orgA Agouni, N Mody, C Owen, A Czopek… - The Biochemical …, 2011 - biochemj.org
*University of Aberdeen, College of Life Sciences and Medicine, Institute of Biological and Environmental
Sciences, Aberdeen, Scotland, UK; †Department of Animal Biology, School of Veterinary
Medicine, University of Pennsylvania, USA; ‡Friedrich Miescher Institute for Biomedical ...
Related articles - View as HTML - All 3 versions

A Mouse Model of [beta]-Thalassemia Shows a Liver-Specific Down-Regulation of Abcc6 Expression

L Martin, V Douet, CM VanWart, MB Heller… - The American Journal of …, 2011 - Elsevier
... mouse model (Hbb th3/+ ). We found a progressive liver-specific down-regulation
of the Abcc6 gene expression and protein levels by quantitative PCR, Western
blotting, and immunofluorescence. The levels of Abcc6 protein ...
Cited by 1 - Related articles - All 4 versions

FGF19 as a Postprandial, Insulin-Independent Activator of Hepatic Protein and Glycogen Synthesis

S Kir, SA Beddow, VT Samuel, P Miller, SF Previs… - Science, 2011 - sciencemag.org
... S3B) or induce sterol regulatory element–binding protein, isoform 1c (SREBP-1c)–dependent
lipogenic gene expression (fig. ... and it uses the alternative Ras-ERK-p90RSK pathway; taken
together, these findings may explain the puzzling observation that liver-specific loss of ...
Cited by 6 - Related articles - All 4 versions

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