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Targeting the anaphase promoting complex: common pathways for viral infection and cancer therapy

L Smolders… - Expert Opinion on Therapeutic …, 2011 - informahealthcare.com
... most viruses targeting the APC/C induce G 2 /M arrest followed by apoptotic cell death and it
is not directly apparent how this ... rounding and subsequent detachment from the epithelial layer,
providing a vehicle for spread of the virus and exposure of other cells to viral infection. ...
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KIR and HLA Genotypes in Control of Viral Infection

M Carrington… - Annual Review of Immunology, 2011 - annualreviews.org
... An early genetic effect of B*57 after HIV infection was originally indicated by survival analyses,
where B*57 protection was most apparent for time ... The effect of B*57 has now been shown for
set point viral load (92), an outcome that occurs much earlier than CD4<200. ...
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Homeostatic proliferation generates long-lived natural killer cells that respond against viral infection

[HTML] from rupress.orgJC Sun, JN Beilke, NA Bezman… - The Journal of …, 2011 - jem.rupress.org
... Il2rg −/− C57BL/6 mice, and the percentage of NK cells was highest at day 5 during homeostatic
expansion, followed by apparent contraction of ... 1 C). Similar to NK cell responses measured during
viral infection (Dokun et al., 2001; Robbins et al., 2004; Sun et al., 2009a), NK ...
Cited by 6 - Related articles - All 3 versions

IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology

[PDF] from northwestern.eduM Pellegrini, T Calzascia, JG Toe, SP Preston… - Cell, 2011 - Elsevier
... Article. IL-7 Engages Multiple Mechanisms to Overcome Chronic Viral Infection and Limit Organ
Pathology. ... Viral titers were determined in the indicated organs, at day 30 post infection, in IL-7
or PBS treated clone 13 infected mice that were depleted of CD4, CD8 or B cells. ...
Cited by 5 - Related articles - All 11 versions

The coxsackie-adenovirus receptor induces an inflammatory cardiomyopathy independent of viral infection

S Yuen, J Smith, L Caruso, M Balan… - Journal of Molecular and …, 2011 - Elsevier
... CAR in the cardiomyocyte during development disrupts the cardiomyocyte intercalated disc
causing a cardiomyopathy apparent in the ... for 2 common causes of viral myocarditis, Group B
coxsackieviruses and adenoviruses, promotes myocarditis in the absence of viral infection. ...
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