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Synthetic Triterpenoid Cyano Enone of Methyl Boswellate (CEMB) activates intrinsic, extrinsic & endoplasmic reticulum stress cell death pathways in tumor cell lines

P Ravanan, R Sano, T Priti, S Ogasawara… - Molecular Cancer …, 2011 - AACR
... CEMB displayed concentration-dependent cytotoxic activity with submicromolar lethal dose 50%
(LD50) values in ten ... dissolved in DMSO at the concentration of 10 mM and aliquots were stored
at -80°C. Stock compound was diluted in culture medium just before cell treatment. ...
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A highly optimized DNA vaccine confers complete protective immunity against high-dose lethal lymphocytic choriomeningitis virus challenge

DJ Shedlock, KT Talbott, C Cress, B Ferraro… - Vaccine, 2011 - Elsevier
... A highly optimized DNA vaccine confers complete protective immunity against high-dose lethal
lymphocytic choriomeningitis virus challenge. ... Furthermore, these responses were capable of
providing 100% protection against a high-dose, normally lethal virus challenge. ...
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[PDF] Cytotoxic effects of opioids on cancer cell lines*

[PDF] from cesar.or.atC Friesen, S Bacher, I Hormann… - International Journal of …, 2011 - cesar.or.at
... as follows: 100 × (experimental dead cells (%) – spontaneous dead cells in medium (%))/100% –
spontaneous dead cells in medium (%)). ... at thera- peutic concentrations (maximum tolerated dose
in patients) and non-therapeutic toxic concentrations (lethal dose) by apoptosis ...
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Toll-like receptor pre-stimulation protects mice against lethal infection with highly pathogenic influenza viruses

[HTML] from virologyj.comK Shinya, T Okamura, S Sueta, N Kasai… - Virology …, 2011 - virologyj.com
... Madin-Darby canine kidney (MDCK) cells were maintained in Dulbecco's modified Eagle's medium
(DMEM) supplemented with 10% fetal calf serum, and 293T human embryonic kidney cells were
maintained in minimal essential medium (MEM) with ... Lethal dose studies in mice. ...
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The Role of Gap Junction Communication and Oxidative Stress in the Propagation of Toxic Effects among High-Dose α-Particle-Irradiated Human Cells

N Autsavapromporn, SM de Toledo, JB Little… - Radiation …, 2011 - rrjournal.org
... Holding cells in the confluent density-inhibited state after irradiation or maintaining them in growth
factor-depleted medium was shown to influence the ... When cells transfected with Cx43-siRNA
were exposed to an 80-cGy lethal dose of α particles and held in confluence for 3 h ...
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