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[HTML] Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator

[HTML] from nih.govM Shuda, HJ Kwun, H Feng, Y Chang… - The Journal of clinical …, 2011 - ncbi.nlm.nih.gov
Merkel cell polyomavirus (MCV) is the recently discovered cause of most Merkel cell carcinomas
(MCCs), an aggressive form of nonmelanoma skin cancer. Although MCV is known to integrate
into the tumor cell genome and to undergo mutation, the molecular mechanisms used by ...
Cited by 1

Immunoediting and persistence of antigen-specific immunity in patients who have previously been vaccinated with NY-ESO-1 protein formulated in ISCOMATRIX™

T Nicholaou, W Chen, ID Davis… - Cancer Immunology, …, 2011 - Springer
Abstract Background NY-ESO-1 protein formulated in ISCOMA- TRIXTM results in CD4?,
CD8? T cell and antibody- mediated immunity. We evaluated persistence of immunity,
relapse-free survival and tumour antigen expression upon relapse in patients vaccinated ...
Related articles - All 2 versions

Risk stratification and validation of prostate specific antigen density as independent predictor of progression in men with low risk prostate cancer during active …

IF San Francisco, L Werner, MM Regan… - The Journal of …, 2011 - Elsevier
Of the cohort 30% progressed during a median of 2.4 years. Three multivariate analyses were
performed. The first analysis used variables only at diagnosis biopsy and revealed that prostate
specific antigen density greater than 0.08 ng/ml/cc and prostate cancer family history ...
Cited by 3 - Related articles - All 7 versions

CXC receptor type 4 promotes metastasis by activating p38 mitogen-activated protein kinase in myeloid differentiation antigen (Gr-1)-positive cells

[HTML] from pnas.orgS Hiratsuka, DG Duda, Y Huang… - Proceedings of the …, 2011 - National Acad Sciences
Increasing evidence suggests that myeloid bone marrow-derived cells (BMDCs) play a critical
role in lung metastasis. Blockade of VEGF receptor 1 (VEGFR1) has been proposed as a potential
strategy to limit myeloid BMDC recruitment to tumors. However, preclinical evidence ...
Cited by 4 - Related articles - All 5 versions

Use of allogeneic cell lines to load antigen presenting cells to elicit or eliminate immune responses

JF Banchereau, F Berard, P Blanco… - US Patent …, 2011 - Google Patents
(12) United States Patent Banchereau et al. USO07988963B1 (10) Patent No.: US 7,988,963
B1 (45) Date of Patent: Aug. 2, 2011 (54) USE OF ALLOGENEIC CELL LINES TO LOAD ANTIGEN
PRESENTING CELLS TO ELICIT OR ELIMINATE IMMUNE RESPONSES (75) Inventors: ...

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