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S Sreeja, TR Santhosh Kumar, BS Lakshmi… - The Journal of …, 2011 - Elsevier
Selective estrogen receptor modulators (SERMs) are estrogen receptor (ER) ligands exhibiting
tissue-specific agonistic or antagonistic biocharacter and are used in the hormonal therapy for
estrogen-dependent breast cancers. Pomegranate fruit has been shown to exert ...
BS Katzenellenbogen, MK Bagchi… - 2011 - ideals.illinois.edu
Estrogens are associated with the development and progression of breast cancer in addition
to their role in normal reproductive physiology, and estrogen receptors (ER) mediate the actions
of estrogen in target tissues by regulating the expression of numerous biologically ...
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B Katzenellenbogen, A Nardulli, D Shapiro… - 2011 - ideals.illinois.edu
Repressor of Estrogen Receptor Activity (REA) is an evolutionarily conserved protein with established
roles in multiple, essential cellular processes including transcription, mitochondrial biogenesis
and replicative senescence. Previous reports suggest that REA is a multifunctional ...
Cached - All 2 versions
BS Katzenellenbogen, AS Belmont, DJ Shapiro… - 2011 - ideals.illinois.edu
Among the first diagnostic tests performed upon finding a tumor in the breast is the determination
of the expression of three proteins: the Estrogen Receptor α (ERα), the Progesterone Receptor
(PR) and Heregulin 2 (HER2). The ER, though often considered responsible for driving ...
Cached - All 2 versions
V Ribas, BG Drew, JA Le… - Proceedings of the …, 2011 - National Acad Sciences
The metabolic syndrome reflects an aggregate of abnormalities including obesity,
inflammation, hypertension, glucose intol- erance, dyslipidemia, and insulin resistance
(1–3), and the clus- tering of these abnormalities is associated with the increased risk of ...

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