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The role of cell surface markers and enamel matrix derivatives on human periodontal ligament mesenchymal progenitor responses in vitro

P Kémoun, S Gronthos, ML Snead, J Rue… - Biomaterials, 2011 - Elsevier
Periodontitis is a chronic-, infectious-disease of the human periodontium that is characterized
by the loss of supporting tissues surrounding the tooth such as the periodontal ligament
(PDL), cementum and alveolar bone. Regeneration of the periodontium is dependent on ...

Induced pluripotent stem cell lines derived from human gingival fibroblasts and periodontal ligament fibroblasts

N Wada, B Wang, NH Lin, AL Laslett… - … of Periodontal …, 2011 - Wiley Online Library
N. Wada1,2,*, B. Wang3,*, N.-H. Lin1, AL Laslett3,4, S. Gronthos2, PM Bartold1 1School of
Dentistry, Colgate Australian Clinical Dental Research Centre, University of Adelaide,
Adelaide, SA, Australia, 2Mesenchymal Stem Cell Group, Division of Haematology, ...
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Promise of periodontal ligament stem cells in regeneration of periodontium

H Maeda, A Tomokiyo, S Fujii, N Wada… - Stem Cell Research & …, 2011 - stemcellres.com
A great number of patients around the world experience tooth loss that is attributed to irretrievable
damage of the periodontium caused by deep caries, severe periodontal diseases or irreversible
trauma. The periodontium is a complex tissue composed mainly of two soft tissues and ...
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Single-Molecule Imaging of BMP4 Dimerization on Human Periodontal Ligament Cells

HW Mi, MC Lee, YC Chiang… - Journal of Dental …, 2011 - jdr.sagepub.com
AbstrAct We expressed bone morphogenetic protein 4 (BMP4) fused with enhanced green fluorescent
protein (BMP4- EGFP) in the secretory pathways of producer cells. Fluorescent EGFP was acquired
only after we interrupted the transport of BMP4-EGFP by culturing cells at a lower ...

Hypoxia inducible factor-1α directly induces the expression of receptor activator of nuclear factor-κB ligand in periodontal ligament fibroblasts

HJ Park, KH Baek, HL Lee, A Kwon, HR Hwang… - Molecules and …, 2011 - Springer
During orthodontic tooth movement, local hypoxia and enhanced osteoclastogenesis are observed
in the com- pression side of periodontal tissues. The receptor activa- tor of nuclear factor-κB ligand
(RANKL) is an osteoblast/ stromal cell-derived factor that is essential for osteoclas- ...
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