推荐同事 机构合作 中文 繁體中文 English 한국어 日本語 Português Español

美国ACCDON公司旗下品牌

021-33361733，021-33632861

chinasupport@letpub.com

登录 注册 新注册优惠

[HTML] TP53 mutations in favorable-risk Wnt/Wingless-subtype medulloblastomas

[HTML] from 171.66.121.246JC Lindsey, RM Hill, H Megahed… - Journal of Clinical …, 2011 - 171.66.121.246
... 1 Of particular note, medulloblastoma is now recognized as comprising distinct molecular disease
subgroups; its primary, consistently identified subgroups are characterized by mutational activation
of the Sonic Hedgehog (SHH subgroup; approximately 25% of cases) or Wnt ...
Cited by 3 - Related articles - All 5 versions

Definition of disease-risk stratification groups in childhood medulloblastoma using combined clinical, pathologic, and molecular variables

[HTML] from 171.66.121.246DW Ellison, M Kocak, J Dalton… - Journal of Clinical …, 2011 - 171.66.121.246
Purpose Medulloblastomas are heterogeneous and include relatively good-prognosis tumors
characterized by Wnt pathway activation, as well as those that cannot be successfully treated
with conventional therapy. Developing a practical therapeutic stratification that allows ...
Cited by 8 - Related articles - All 6 versions

Molecular basis of copper transport: cellular and physiological functions of Menkes and Wilson disease proteins (ATP7A and ATPB)

D Kramer, R Llanos… - Metal ions and neurodegenerative …, 2011 - deakin.edu.au
Eukaryotic cells prevent copper-induced, free radical damage to cell components by employing
copper-binding proteins and transporters that minimize the likelihood of free copper ions existing
in the cell. In the cell, copper is actively transported from the cytoplasm during the ...
Cited by 3 - Related articles - Cached - All 3 versions

[CITATION] Scriver's Online Metabolic and Molecular Bases of Inherited Disease

D Valle, AL Beaudet, B Vogelstein, KW Kinzler… - 2011
Cited by 2 - Related articles

Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection

E Valkov, A Stamp, F DiMaio… - Proceedings of the …, 2011 - National Acad Sciences
Toll-like receptors (TLRs) are a family of single-pass trans- membrane proteins that mediate
innate immune responses to microbial stimuli such as bacterial lipids and nonself nucleic acids
(1, 2). These molecules bind directly to the extracellular domains of the receptors and ...

联系我们 | 站点地图 | 友情链接 | 授权代理商 | 加入我们

© 2010-2024 中国: LetPub上海分公司    网站备案号：沪ICP备10217908号-1    沪公网安备号：31010402006960

增值电信业务经营许可证：沪B2-20211595

礼翰商务信息咨询（上海）有限公司      办公地址：上海市徐汇区漕溪北路88号圣爱大厦1803室

United States: Tel: 1-781-202-9968 Address: 400 5th Ave, Suite 530, Waltham, Massachusetts 02451