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… -412 DPY19L2, its mutation in about half globozoospermiaP-413 The study of aneuploidy on polar bodies predicts efficiently the chromosomal status of the …

B Acar-Perk, J Weimer, K Koch, A Salmassi… - Human …, 2011 - ESHRE
Results: 10648 AID cycles were performed from January,2007 to September, 2009 in our Hospital
and resulted in 2364 clinical pregnancies,the clinical preg- nancy rate was 22.20%. All 10648
cycles were followed up completely and the follow-up rate was 100%.The average age of ...

Mechanisms that Promote and Suppress Chromosomal Translocations in Lymphocytes.

M Gostissa, FW Alt… - Annual review of immunology, 2011 - ncbi.nlm.nih.gov
Recurrent chromosomal translocations are characteristic features of many types of cancers, especially
lymphomas and leukemias. Several basic mechanistic factors are required for the generation
of most translocations. First, DNA double-strand breaks (DSBs) must be present ...
Cited by 3 - Related articles

Chromosomal instability: A lack of new origins drives fragility

N McCarthy - Nature Reviews Cancer, 2011 - nature.com
Chromosomal fragile sites initially came to the attention of the cancer research community because
they were identified as sites of chromosomal breakpoints in tumours. Why these regions are
more fragile than others has taken a while to sort out at the molecular level. New data ...

Extranuclear protection of chromosomal DNA from oxidative stress

[HTML] from pnas.orgS Vanderauwera, N Suzuki… - Proceedings of the …, 2011 - National Acad Sciences
Eukaryotic organisms evolved under aerobic conditions subjecting nuclear DNA to damage provoked
by reactive oxygen species (ROS). Although ROS are thought to be a major cause of DNA
damage, little is known about the molecular mechanisms protecting nuclear DNA from ...
Cited by 5 - Related articles - All 6 versions

Manipulating piggyBac Transposon Chromosomal Integration Site Selection in Human Cells

C Kettlun, DL Galvan, AL George Jr, A Kaja… - Molecular …, 2011 - nature.com
The ability to direct gene delivery to a user-defined chromosomal location would greatly improve
gene transfer applications. The piggyBac transposon system is a nonviral gene transfer system
proven effective in a variety of cells and tissues, including human cells. We fused a highly ...
All 3 versions

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