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The orally bioavailable met inhibitor PF‐2341066 inhibits osteosarcoma growth and osteolysis/matrix production in a xenograft model

ER Sampson, BA Martin, AE Morris… - Journal of Bone and …, 2011 - Wiley Online Library
Osteosarcoma (OS) is the most common primary bone tumor in children and adolescents. Ninety
percent of patients who present with metastatic and 30% to 40% of patients with nonmetastatic
disease experience relapse, creating an urgent need for novel therapeutic strategies. The ...
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Breast cancer cell epidermal growth factor receptor signaling and osteolysis

JL Gilmore, A Robling… - Bone, 2011 - journals.elsevierhealth.com
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ARTICLE. Breast cancer cell epidermal growth factor receptor signaling and osteolysis ...
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2-Methoxyestradiol Analogue ENMD-1198 Reduces Breast Cancer-Induced Osteolysis and Tumor Burden Both In Vitro and In Vivo

TJA Snoeks, IM Mol, I Que, EL Kaijzel… - Molecular Cancer …, 2011 - AACR
It has been estimated that 70% of advanced breast cancer patients will face the complication
of bone metastases. Three processes are pivotal during bone metastatic growth of breast
cancer, namely, tumor cell proliferation, angiogenesis, and osteolysis. During ...
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[CITATION] Assessment of signalling downstream of the mutant rank protein that causes familial expansile osteolysis

DJG Mellis, A Duthie, MJ Rogers, MH Helfrich… - Bone, 2011 - Elsevier

[CITATION] Breast cancer cell epidermal growth factor receptor signaling and osteolysis

NK Nickerson*, JL Gilmore, A Robling… - Bone, 2011 - Elsevier

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