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Development of t (8; 21) and RUNX1-RUNX1T1 in the Philadelphia-positive clone of a patient with chronic myelogenous leukemia: additional evidence for multiple …

V Najfeld, N Wisch, J Mascarenhas, L Issa… - Cancer Genetics, 2011 - Elsevier
... A diagnosis of blast transformation of CML was made (Figure 1). In January 2010, the patient
was given low-dose nilotinib, as well as decitabine at the dose of 20 mg/m 2 , for 4 consecutive ...
Abbreviations: AML, acute myeloid leukemia; BC, blast crisis; CP, chronic phase; F ...
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… within BCR-ABL kinase domain confers imatinib resistance: sequential analysis of the clonal evolution in a patient with chronic myeloid leukemia in blast crisis

K Sakai, Y Ishikawa, Y Mori, M Kobayashi… - International journal of …, 2011 - Springer
... 123 Page 6. 14. Zhang SJ, Ma LY, Huang QH, et al. Gain-of-function mutation of
GATA-2 in acute myeloid transformation of chronic myeloid leukemia. Proc Natl Acad
Sci USA. 2008;105:2076–81. 15. Ishikawa Y, Kiyoi H, Watanabe K, et al. ...
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[HTML] Uncommon of the Uncommon: Low-Grade Myelodysplastic Syndrome Evolving Into Chronic Myelogenous Leukemia

[HTML] from ascopubs.orgL Zhang, JM Bennett, X Zhang… - Journal of Clinical …, 2011 - jco.ascopubs.org
... subcategorized as refractory cytopenia with multilineage dysplasia and ring sideroblasts,
progressing into an accelerated phase of CML. ... in de novo MDS or therapy-related MDS at the
beginning, during, or right before transformation to AML or acute lymphoblastic leukemia ...
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Three decades of transplantation for chronic myeloid leukemia: what have we learned?

[HTML] from hematologylibrary.orgJ Pavlů, RM Szydlo, JM Goldman… - Blood, 2011 - bloodjournal.hematologylibrary.org
... blasts after infusion of leukocytes from a CML donor into a patient with acute leukemia and
intractable ... first to collect Ph-negative peripheral stem cells after intensive chemotherapy in a patient
in chronic phase and to use them later for autografting after blast transformation. ...
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[PDF] are associated with the autosomal dominant and GATA2 Mutations in

[PDF] from hematologylibrary.orgDDH Cuellar-Rodriguez, SM Holland… - 2011 - bloodjournal.hematologylibrary.org
... Zhang et al reported a GATA2 gain of function somatic mutation, L359V, occurring in acute
transformation of chronic myeloid leukemia.13 The recently described syndrome of
homozygous recessive IRF8 deficiency lacked circulating monocytes ...
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