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JS Brockenbrough, T Souquet… - Journal of Nuclear …, 2011 - Soc Nuclear Med
We report the first, to our knowledge, findings describing the relationships between both static
and dynamic analysis parameters of 3′-deoxy-3′- 18 F-fluorothymidine ( 18 F-FLT) PET and
the expression of the proliferation marker Ki-67, and the protein expression and ...
L Wang, R Sun… - Antimicrobial Agents and …, 2011 - Am Soc Microbiol
Mitochondrial thymidine kinase 2 (TK2) is a key enzyme in the salvage of pyrimidine deoxynucleosides
needed for mitochondrial DNA synthesis. TK2 phosphorylates thymidine (dThd), deoxycytidine
(dCyd), and many other antiviral pyrimidine nucleoside analogs. Zidovudine (AZT) is the ...
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T Shiota, W Lixin, M Takayama-Ito, I Iizuka… - Antiviral Research, 2011 - Elsevier
Antiviral-resistant herpesvirus infection has become a great concern for immunocompromised
patients. Herpes simplex virus type 1 (HSV-1) infections are treated with viral thymidine kinase
(vTK)-associated drugs such as acyclovir (ACV), and most ACV-resistance (ACV r ) is due ...
All 2 versions
T Radivoyevitch, B Munch-Petersen… - … and Nucleic Acids, 2011 - Taylor & Francis
The mitochondrial enzyme thymidine kinase 2 (TK2) phosphorylates deoxythymidine (dT) and
deoxycytidine (dC) to form dTMP and dCMP, which in cells rapidly become the negative-feedback
end-products dTTP and dCTP. TK2 kinetic activity exhibits Hill coefficients of 0.5 ...
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C Di Cresce, R Figueredo, PJ Ferguson… - … of Pharmacology and …, 2011 - ASPET
Page 1. JPET #183178 1 Title Page Title: Combining siRNAs Targeting Thymidylate Synthase
and Thymidine Kinase 1 or 2 Sensitizes Human Tumor Cells to 5FUdR and Pemetrexed* ... with
Tween 20; TK, Thymidine Kinase (general); TK1, cytosolic thymidine kinase 1; ...
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