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Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance in Toxoplasma gondii

SC Nair, CF Brooks, CD Goodman… - The Journal of …, 2011 - jem.rupress.org
Apicomplexa are important pathogens that include the causative agents of malaria,
toxoplasmosis, and cryptosporidiosis. Apicomplexan parasites contain a relict chloroplast, the
apicoplast. The apicoplast is indispensable and an attractive drug target. The apicoplast ...
Cited by 1 - Related articles - All 3 versions

[CITATION] Regulation of the amyloid precursor protein processing by the Nuclear Factor-kappa B

L Chami, V Buggia-Prevot… - Alzheimer's and Dementia, 2011 - Elsevier

ADP ribosylation factor 6 (ARF6) controls amyloid precursor protein (APP) processing by mediating the endosomal sorting of BACE1

[HTML] from nih.govR Sannerud, I Declerck, A Peric… - Proceedings of the …, 2011 - National Acad Sciences
Amyloid β (Aβ) peptides, the primary constituents of senile plaques and a hallmark in Alzheimer's
disease pathology, are generated through the sequential cleavage of amyloid precursor protein
(APP) by β-site APP cleaving enzyme 1 (BACE1) and γ-secretase. The early endosome is ...

Amyloid Precursor Protein in Alzheimer's Disease

R O'Brien - Annual Review of Neuroscience, 2011 - annualreviews.org
Alzheimer's disease (AD), the leading cause of dementia worldwide, is characterized by the accumulation
of the β-amyloid peptide (Aβ) within the brain along with hyperphosphorylated and cleaved forms
of the microtubule-associated protein tau. Genetic, biochemical, and behavioral research ...
Cited by 1 - Related articles - All 2 versions

Characterizing Heterogeneous Properties of Cerebral Aneurysms With Unknown Stress-Free Geometry: A Precursor to In Vivo Identification

[PDF] from uiowa.eduX Zhao, ML Raghavan… - Journal of Biomechanical Engineering, 2011 - link.aip.org
Knowledge of elastic properties of cerebral aneurysms is crucial for understanding the biomechanical
behavior of the lesion. However, characterizing tissue properties using in vivo motion data presents
a tremendous challenge. Aside from the limitation of data accuracy, a pressing issue is ...
Cited by 1 - Related articles - All 5 versions

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