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Comparison of Urine Cotinine and the Tobacco-Specific Nitrosamine Metabolite 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol (NNAL) and Their Ratio to Discriminate …

ML Goniewicz, MD Eisner… - Nicotine & Tobacco …, 2011 - ntr.oxfordjournals.org
Objectives: Cotinine is the most widely used biomarker to distinguish active versus passive
smoking. However, there is an overlap in cotinine levels when comparing light or occasional
smokers versus heavily exposed passive smokers. 4-(methylnitrosamino)-1-(3-pyridyl)-1- ...
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Genetic variability in the metabolism of the tobacco‐specific nitrosamine 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone (NNK) to 4‐(methylnitrosamino)‐1‐(3‐ …

M Ter‐Minassian, K Asomaning… - … Journal of Cancer, 2011 - Wiley Online Library
Page 1. 1 Genetic variability in the metabolism of the tobacco-specific nitrosamine 4-
(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) to 4-(methylnitrosamino)-1-(3- ... Key words:
NNK, NNAL, tobacco specific nitrosamine, genetic polymorphism, HSD11B1 Abbreviations used: ...
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Occurrence of nine nitrosamines and secondary amines in source water and drinking water: potential of secondary amines as nitrosamine precursors

W Wang, S Ren, H Zhang, J Yu, W An, J Hu… - Water Research, 2011 - Elsevier
Due to their high carcinogenicity, the control of nitrosamines, a group of disinfection by-products
(DBPs), is an important issue for drinking water supplies. In this study, a method using ultra-performance
liquid chromatography-electrospray ionization tandem mass spectrometry was improved ...

Whole-genome gene expression modifications associated with nitrosamine exposure and micronucleus frequency in human blood cells

DGAJ Hebels, DGJ Jennen… - …, 2011 - Oxford Univ Press
N-nitroso compounds (NOCs) are suspected human carcinogens and relevant in human
exposure. NOCs also induce micronuclei (MN) formation in vivo. Since lymphocytic MN represent
a validated biomarker of human cancer risk, establishing a link between NOC exposure ...
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[HTML] GC/MS Determination of N-butyl-N-(3-carboxypropyl) Nitrosamine (BCPN) in Bladder Cancers-The Skewed Molecular Interaction Caused Retention Time …

[HTML] from omicsonline.orgCL Hsieh, HE Wang, YB Ker, CC Peng… - J Anal Bioanal …, 2011 - omicsonline.org
... Research Article, Open Access. GC/MS Determination of N-butyl-N-(3-carboxypropyl)
Nitrosamine (BCPN) in Bladder Cancers - The Skewed Molecular Interaction Caused
Retention Time Shift. Chiu-Lani Hsieh 1 , Huir-Er Wang ...
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