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Brivanib, a Dual FGF/VEGF inhibitor, is active both first and second line against mouse pancreatic neuroendocrine tumors developing adaptive/evasive resistance to …

E Allen, IB Walters… - Clinical Cancer Research, 2011 - AACR
Experimental Design: An anti-VEGFR2 monoclonal antibody (DC101), an inhibitor of FGF signaling
(FGF ligand trap), sorafenib, and brivanib were comparatively evaluated in first-line monotherapy
in short and longer term fixed endpoint intervention trials in the RIP-Tag2 mouse model of ...
Cited by 2

POSTER VIEWING SESSION-REPRODUCTIVE (EPI) GENETICSP-406 Distinct isolation of embryoblast and trophoblast cells from mouse blastocyst for genetic …

B Acar-Perk, J Weimer, K Koch, A Salmassi… - Human …, 2011 - ESHRE
Results: 10648 AID cycles were performed from January,2007 to September, 2009 in our Hospital
and resulted in 2364 clinical pregnancies,the clinical preg- nancy rate was 22.20%. All 10648
cycles were followed up completely and the follow-up rate was 100%.The average age of ...

Mouse models of advanced spontaneous metastasis for experimental therapeutics

G Francia, W Cruz-Munoz, S Man, P Xu… - Nature Reviews …, 2011 - nature.com
An enduring problem in cancer research is the failure to reproduce highly encouraging preclinical
therapeutic findings using transplanted or spontaneous primary tumours in mice in clinical trials
of patients with advanced metastatic disease. There are several reasons for this, ...
Cited by 9 - Related articles - All 4 versions

CD4+ CD25+ Foxp3+ Regulatory T Cells Promote Th17 Cells In Vitro and Enhance Host Resistance in Mouse Candida albicans Th17 Cell Infection Model

[PDF] from nyu.eduP Pandiyan, HR Conti, L Zheng, AC Peterson… - Immunity, 2011 - Elsevier
Th17 cells and CD4 + CD25 + Foxp3 + regulatory T (Treg) cells are thought to promote and suppress
inflammatory responses, respectively. Here we explore why under Th17 cell polarizing
conditions, Treg cells did not suppress, but rather upregulated, the expression of ...
Cited by 7 - Related articles - All 3 versions

[HTML] Cardiac neural crest orchestrates remodeling and functional maturation of mouse semilunar valves

[HTML] from nih.govR Jain, KA Engleka, SL Rentschler… - The Journal of …, 2011 - ncbi.nlm.nih.gov
Congenital anomalies of the aortic valve are common and are associated with progressive valvular
insufficiency and/or stenosis. In addition, aneurysm, coarctation, and dissection of the ascending
aorta and aortic arch are often associated conditions that complicate patient management ...
Cited by 2 - Related articles - All 4 versions

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