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Guidance for understanding solubility as a limiting factor for selecting the upper test concentration in the OECD In Vitro Micronucleus Assay Test Guideline No. 487

MJ Aardema, S Galloway, E Zeiger… - … /Genetic Toxicology and …, 2011 - Elsevier
The OECD guideline for the in vitro mammalian cell micronucleus test (OECD 487) was recently
adopted in July 22, 2010. Since its publication, it has become apparent that the guidance for
testing chemicals where solubility is a limiting factor can be interpreted in a variety of ...
All 2 versions

In vivo Genotoxicity Evaluation of Atrazine and Atrazine Based Herbicide on Fish Carassius auratus Using the Micronucleus Test and the Comet Assay

T Cavas - Food and Chemical Toxicology, 2011 - Elsevier
Atrazine is a selective triazine herbicide used to control broadleaf and grassy weeds mainly in
corn, sorghum, sugarcane, pineapple, and other crops, and in conifer reforestation planting
fields. It has been showed that atrazine is one of the most frequently detected pesticides ...
All 2 versions

Nuclear damage in peripheral lymphocytes of obese and overweight Italian children as evaluated by the γ-H2AX focus assay and micronucleus test

R Scarpato, C Verola, B Fabiani, V Bianchi… - The FASEB Journal, 2011 - FASEB
Childhood obesity, often characterized by a chronic low-grade inflammation, has been associated
with an increased risk of developing some types of cancer later in life. Nuclear γ-H2AX foci represent
the first detectable response of cells to DNA tumorigenesis lesions, such as the double- ...
Cited by 2 - Related articles - All 3 versions

Bacterial reverse mutation test and micronucleus test of fucoxanthin oil from microalgae.

K Iio, Y Okada… - … eiseigaku zasshi. Journal of the Food …, 2011 - ncbi.nlm.nih.gov
Fucoxanthin-containing oil extracted from microalga, Chaetoseros sp., was aubjected to genotoxicity
studies, the bacterial reverse mutation test and the micronucleus test in mice. The number of
revertant colonies in fucoxanthin oil-treated plates of all strains tested was less than twice ...

Assessment of DNA damage in coal open-cast mining workers using the cytokinesis-blocked micronucleus test and the comet assay

G Leon-Mejia, L Espitia-Perez… - Science of the Total …, 2011 - Elsevier
Coal mining is one of the most important causes of environmental pollution, as large quantities
of coal dust particles are emitted. Colombia-South America has large natural coal reserves and
“El Cerrejón” is the world's largest open-cast mine located in the northern department of ...
All 4 versions

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