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Histamine restricts cancer: nothing to sneeze at

B Ruffell… - Nature Medicine, 2011 - nature.com
Tumors do not develop in spite of their 'host' but rather with the combined support of normal cells
that comprise the tumor stroma, including fibroblasts and other niche-defining cells, vascular
cells and various leukocyte populations. These cells participate in a maladaptive immune ...
All 3 versions

TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch

[PDF] from wustl.eduSR Wilson, KA Gerhold, A Bifolck-Fisher… - Nature …, 2011 - nature.com
Itch, the unpleasant sensation that evokes a desire to scratch, accompanies numerous skin and
nervous system disorders. In many cases, pathological itch is insensitive to antihistamine
treatment. Recent studies have identified members of the Mas-related G protein–coupled ...
Cited by 2 - Related articles - All 4 versions

Histamine H4 receptor activation enhances LPS‐induced IL‐6 production in mast cells via ERK and PI3K activation

P Desai… - European Journal of Immunology, 2011 - Wiley Online Library
The histamine H 4 receptor (H 4 R) has been implicated in numerous inflammatory
functions. Here it is shown that the receptor can mediate cytokine production from mast cells.
Histamine and an H 4 R agonist, JNJ 28610244, induced the production of IL-6 in mouse ...
Related articles - All 2 versions

BAM8–22 Peptide Produces Itch and Nociceptive Sensations in Humans Independent of Histamine Release

[HTML] from cjb.netP Sikand, X Dong… - The Journal of Neuroscience, 2011 - neuro.cjb.net
Chronic itch accompanying many dermatological, neurological, and systemic diseases is unresponsive
to antihistamines. Our knowledge of endogenous chemicals that evoke histamine-independent
itch and their molecular targets is very limited. Recently it was demonstrated in behavioral ...
Cited by 1 - Related articles - All 4 versions

Antitumor properties of histamine in vivo

FB Thoren, J Aurelius… - Nature Medicine, 2011 - nature.com
Yang et al. 1 recently reported that mice with histamine deficiency due to genetic disruption of
histidine decarboxylase (HDC) show impaired myeloid cell differentiation. The absence of histamine
formation caused accumulation of immature myeloid cells (IMCs), which was ...
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