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Best Practices for Clinical Pathology Testing in Carcinogenicity Studies

JK Young, RL Hall, P O'Brien… - Toxicologic …, 2011 - tpx.sagepub.com
... Carcinogenicity Test . ... The Chronic Toxicity Test, Test of Impact on Reproductive Potential
and Future Generations, Teratogenicity Test, Mutagenicity Test, Carcinogenicity Test, Test
of in vivo Fate, and Pharmacological Test for Chemical Substances . ...
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Historical perspective on the use of animal bioassays to predict carcinogenicity: Evolution in design and recognition of utility

LA Beyer, BD Beck… - Critical Reviews in …, 2011 - informahealthcare.com
... OECD has also published numerous guidelines for the testing of chemicals (eg, Test
Guideline 453: Combined Chronic Toxicity/Carcinogenicity Studies; OECD, 2009a), which
was first published in 1981 and updated in 2009 (OECD, 2009b). ...
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Acute toxicity of CCR5 antagonist C25P polypeptide in mice and its carcinogenicity in vitro.

XM Mo, HX Sun… - Nan fang yi ke da xue xue bao= …, 2011 - ncbi.nlm.nih.gov
... pathological examination. The carcinogenicity of C25P polypeptide in vitro was
evaluated in cultured cell lines by chromosome aberration test, cell transformation
test and non-anchorage dependent growth test. RESULTS: No ...

An analysis of pharmaceutical experience with decades of rat carcinogenicity testing

FD Sistare, D Morton, C Alden… - Toxicologic …, 2011 - tpx.sagepub.com
... The value of ±25% was chosen to allow for and accommodate slight differences in
dose level selection, lot and batch number of test articles, and dose formulation
differences between chronic toxicology and carcinogenicity studies. ...
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[HTML] Docking study of HIV-1 reverse transcriptase with phytochemicals

[HTML] from nih.govA Seal, R Aykkal, RO Babu… - Bioinformation, 2011 - ncbi.nlm.nih.gov
... Caco-2cell permeability, Madin-Darby Canine Kidney Cell Permeability (MDCK), Human Intestinal
Absortion (HIA), Skin Permeability, Blood-Brain Barrier (BBB) penetration were also calculated
for the molecules along with the mutagenicity and carcinogenicity test based on ...
Cited by 1 - Related articles - All 6 versions

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