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Multifactorial Induction of an Orphan PKS-NRPS Gene Cluster in Aspergillus terreus

[PDF] from aspergillus.org.ukM Gressler, C Zaehle, K Scherlach, C Hertweck… - Chemistry & Biology, 2011 - Elsevier
Mining the genome of the pathogenic fungus Aspergillus terreus revealed the presence of an
orphan polyketide-nonribosomal-peptide synthetase (PKS-NRPS) gene cluster. Induced expression
of the transcriptional activator gene adjacent to the PKS-NRPS gene was not sufficient for ...
Cited by 2 - Related articles - All 4 versions

In Vitro Activity and In Vivo Efficacy of Posaconazole in Treatment of Murine Infections by Different Isolates of the Aspergillus terreus Complex

V Salas, FJ Pastor, MM Rodriguez… - Antimicrobial Agents …, 2011 - Am Soc Microbiol
Posaconazole (PSC) is an antifungal drug recommended as an alternative for the treatment of
invasive aspergillosis in patients who are refractory or intolerant to primary antifungal
therapy. We have evaluated the in vitro activity of PSC against 21 strains of the ...
Cited by 1 - Related articles - All 3 versions

Aspergillus terreus accessory conidia are multinucleated, hyperpolarizing structures that display differential dectin staining and can induce heightened inflammatory …

E Deak, M Nelson, Y Hernández-Rodríguez… - Virulence, 2011 - ncbi.nlm.nih.gov
In addition to phialidic conidia (PC), A. terreus produces accessory conidia (AC) both in vitro
and in vivo. AC are distinct from PC in cell surface architecture, with the AC surfaces displaying
more β-glucan, a molecule that can be a trigger for the induction of inflammatory ...
Cited by 1 - All 5 versions

Monoclonal antibodies to hyphal exoantigens derived from the opportunistic pathogen, Aspergillus terreus

AP Nayak, BJ Green, E Janotka… - Clinical and Vaccine …, 2011 - Am Soc Microbiol
Page 1. 1 Monoclonal antibodies to hyphal exoantigens derived from the opportunistic 1 pathogen,
Aspergillus terreus 2 3 ... Fax: (304) 285-6126. E-mail: zec1@cdc.gov. 26 27 28 Key words:
Aspergillus terreus, immunoglobulin G, monoclonal antibody, exoantigen 29 30 ...
All 2 versions

Environmental and clinical epidemiology of Aspergillus terreus: data from a prospective surveillance study

M Rüping, S Gerlach, G Fischer… - Journal of Hospital …, 2011 - Elsevier
Aspergillus terreus may be resistant to amphotericin B and is associated with significant morbidity
and mortality in immunocompromised patients. Local incidence is influenced by the density of
airborne Aspergillus spp. spores which may in turn depend on meteorological factors. ...
Related articles - All 3 versions

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