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Amyotrophic Lateral Sclerosis

O Hardiman - Neurodegenerative Disorders, 2011 - Springer
Abstract Amyotrophic lateral sclerosis or motor neuron disease is a progressive motor system
degeneration. Extra motor involvement also occurs, primarily in the form of execu- tive
dysfunction. Up to 15% of those with ALS also develop frontotemporal dementia. The ...
Related articles - All 4 versions

Amyotrophic lateral sclerosis

WS Johnston, K Hoskins… - Neurology, 2011 - AAN Enterprises
The patient's wife, Anne Smith, reports that her husband Glen has suffered weakness of the hands
and then arms gradually over the last year. Three months ago, he consulted a neurologist, who
performed numerous investigations, then told Glen he had ALS or Lou Gehrig's disease. ...
Cited by 2 - Related articles

Amyotrophic lateral sclerosis

MC Kiernan, S Vucic, BC Cheah, MR Turner… - The Lancet, 2011 - Elsevier
Amyotrophic lateral sclerosis (ALS) is an idiopathic, fatal neurodegenerative disease of the human
motor system. In this Seminar, we summarise current concepts about the origin of the
disease, what predisposes patients to develop the disorder, and discuss why all cases of ...
Cited by 8 - Related articles - All 7 versions

From symptom onset to a diagnosis of amyotrophic lateral sclerosis/motor neuron disease (ALS/MND): Experiences of people with ALS/MND and family carers-a …

MR O'Brien, B Whitehead… - Amyotrophic Lateral …, 2011 - informahealthcare.com
Our objectives were to explore the personal perspectives of the diagnostic experience for people
with ALS/MND and their family carers identifying issues that could impact positively or negatively
on these experiences. We conducted a qualitative study with face-to-face interviews to ...
Cited by 1 - Related articles - All 3 versions

Identification of compounds protective against G93A-SOD1 toxicity for the treatment of amyotrophic lateral sclerosis

[PDF] from northwestern.eduR Benmohamed, AC Arvanites… - … Lateral Sclerosis, 2011 - informahealthcare.com
The underlying cause of amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative
disorder, remains unknown. However, there is strong evidence that one pathophysiological
mechanism, toxic protein misfolding and/or aggregation, may trigger motor neuron ...
Cited by 2 - Related articles - All 4 versions

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