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Senile Nephrosclerosis–Does It Explain the Decline in Glomerular Filtration Rate with Aging?

AD Rule, LD Cornell… - Nephron Physiology, 2011 - content.karger.com
Nephrosclerosis can be defined by the presence of glomerulosclerosis, tubular atrophy, interstitial
fibrosis, and arteriosclerosis on renal biopsy. Chronic kidney disease is identified clinically by
a reduction in glomerular filtration rate (GFR) and has been characterized histologically ...

The role of bone morphogenetic protein-5 (BMP-5) in human nephrosclerosis.

CP Bramlage, GA Müller, B Tampe… - Journal of …, 2011 - ncbi.nlm.nih.gov
Background: Bone morphogenetic protein-5 (BMP-5) has been shown to be essential for
nephrogenesis. Its role in adult kidney and in patients with hypertensive nephrosclerosis is still
unknown. Methods: BMP-5 expression was evaluated by immunostaining and real-time ...

Hypertensive nephrosclerosis.

T Krummel, D Bazin, AL Faller… - Presse medicale (Paris, …, 2011 - ncbi.nlm.nih.gov
Hypertensive nephrosclerosis is the leading cause of end stage renal disease (ESRD) in
France, however, in prospective clinical trials of hypertension, ESRD accounts only for a small
fraction of all events (incidence rate 0.2 to 0.4% by year). Hypertensive nephrosclerosis is ...

ADAMTS13—marker of contractile phenotype of arterial smooth muscle cells lost in benign nephrosclerosis

CL Bockmeyer, V Forstmeier, F Modde… - Nephrology Dialysis …, 2011 - ERA-EDTA
Background. Hypertensive nephrosclerosis alone and in combination with other renal diseases
is a leading cause of terminal renal insufficiency. Histologic lesions manifest as benign nephrosclerosis
(bN) with arteriolar hyalinosis and later fibrosis. Procoagulant micromilieus have been ...
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Expression of ACE and ACE2 in Patients with Hypertensive Nephrosclerosis

G Wang, FM Lai, BC Kwan, KB Lai… - Kidney and Blood …, 2011 - content.karger.com
... with Hypertensive Nephrosclerosis ... Introduction Hypertensive nephrosclerosis (HTN) is an
important complication of systemic hypertension and a major cause of end-stage renal disease
(ESRD) [1, 2] . However, the pathogenesis of HTN is not completely clarified. ...
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