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Radiosensitization of Human Cervical Cancer Cells by Inhibiting Ribonucleotide Reductase: Enhanced Radiation Response at Low-Dose Rates

CA Kunos, VC Colussi, J Pink… - International Journal of …, 2011 - Elsevier
... Comparing two clinically relevant dose rates (ie, >300 cGy/min for conventional external beam
radiotherapy and 67 cGy/h for low ... To discover whether 3-AP hampered the activity of RNR during
conditions of continuous low-dose-rate irradiation, cells received no treatment (0 cGy ...
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[PDF] Pilot Study on Continuous Hyperfractionated Accelerated Radiotherapy (CHART) and High Dose Rate Brachytherapy in Locally Advanced Cervical Cancer

[PDF] from omicsonline.orgBM Biswal, NM Ahmad, ZA Hanafia… - J Cancer Sci …, 2011 - omicsonline.org
... documented equi-effectiveness of HDR in place of classical low dose rate brachytherapy. ... and
its modifications have been tried to improve radiation dose and decrease ... co- workers from Mount
Vernon Hospital London have popularized continuous hyperfractionated accelerated ...
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Semicontinuous Low-Dose-Rate Teletherapy for the Treatment of Recurrent Glial Brain Tumors: Final Report of a Phase I/II Study

ML Siker, SY Firat, W Mueller, H Krouwer… - International Journal of …, 2011 - Elsevier
... An alternative explanation suggests that protracted low-dose-rate (LDR) irradiation is biologically
distinct compared to short-term high-dose-rate fractionated irradiation (23). ... Radiotherapy was
delivered 6 to 8 hours/day at a dose rate of 40 to 50 cGy/hour, delivering 30 to ...
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… -related events at 10 years for intermediate-and high-risk prostate cancer patients treated with hypofractionated high-dose-rate boost and external beam radiotherapy

AA Martinez, J Gonzalez, H Ye, M Ghilezan… - International Journal of …, 2011 - Elsevier
... The HDR dose fractionation was divided into two dose levels. The prostate biologically
equivalent dose (BED) low-dose-level group received <268 Gy, and the high-dose group
received >268 Gy . ... The 10-year biochemical failure rate of 43.1% vs. ...
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Comparison of cellular damage response to low-dose-rate 125I seed irradiation and high-dose-rate gamma irradiation in human lung cancer cells

H Chen, Y Bao, L Yu, R Jia, W Cheng… - Brachytherapy, 2011 - Elsevier
... two orders of magnitude lower than that of external radiotherapy, and it also varies with time and
spatial distribution of 125 I seeds although the total dosage might be high. Previous studies [3]
and [4] showed that in the presence of continuous low-dose-rate (LDR) irradiation ...
Related articles - All 2 versions

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