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Roscovitine Inhibits EBNA1 Serine 393 Phosphorylation, Nuclear Localization, Transcription, and Episome Maintenance

MS Kang, EK Lee, V Soni, TA Lewis… - Journal of …, 2011 - Am Soc Microbiol
Latent Epstein-Barr virus (EBV) infection causes human lymphomas and carcinomas. EBV usually
persists as an episome in malignant cells. EBV episome persistence, replication, and gene expression
are dependent on EBNA1 binding to multiple cognate sites in oriP. To search for ...
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The Internal Kaposi's Sarcoma-Associated Herpesvirus LANA Regions Exert a Critical Role on Episome Persistence

E De Leon Vazquez… - Journal of Virology, 2011 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV) latency-associated nuclear antigen
(LANA) is a 1,162-amino-acid protein that acts on viral terminal repeat (TR) DNA to mediate KSHV
episome persistence. The two essential components of episome persistence are DNA ...
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[HTML] The stealth episome: suppression of gene expression on the excised genomic island PPHGI-1 from Pseudomonas syringae pv. phaseolicola

[HTML] from plos.orgSAC Godfrey, HC Lovell, JW Mansfield, DS Corry… - PLoS pathogens, 2011 - dx.plos.org
Bacterial pathogens evolve rapidly through the transfer of large segments, or genomic islands
(GIs), of DNA. We study the mobility of an island named PPHGI-1 in Pseudomonas syringae
pv. phaseolicola that causes halo-blight disease of bean. The exposure of P. syringae pv. ...
Cited by 3 - Related articles - Cached - All 4 versions

HPV Episome Levels are Potently Decreased by Pyrrole-Imidazole Polyamides

TG Edwards, KJ Koeller, U Slomczynska, K Fok… - Antiviral Research, 2011 - Elsevier
Human papillomavirus (HPV) causes cervical cancer and other hyperproliferative diseases. There
currently are no approved antiviral drugs for HPV that directly decrease viral DNA load and that
have low toxicity. We report the potent anti-HPV activity of two N-methylpyrrole-imidazole ...
All 2 versions

[HTML] Bocavirus Episome in Infected Human Tissue Contains Non-Identical Termini

[HTML] from plos.orgA Kapoor, M Hornig, A Asokan, B Williams… - PloS one, 2011 - dx.plos.org
Human bocaviruses (HBoV) are highly prevalent human infections whose pathogenic potential
remains unknown. Recent identification of the first non-human primate bocavirus [1] in captive
gorillas raised the possibility of the persistent nature of bocavirus infection. To ...
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