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Hypomorphic mutation in the site-1 protease Mbtps1 endows resistance to persistent viral infection in a cell-specific manner

DL Popkin, JR Teijaro, BM Sullivan, S Urata… - Cell Host & Microbe, 2011 - Elsevier
The prototypic arenavirus lymphocytic choriomeningitis virus (LCMV), which naturally
persists in rodents, represents a model for HIV, HBV, and HCV. Cleavage of the viral
glycoprotein precursor by membrane-bound transcription factor peptidase, site 1 (Mbtps1 ...
Cited by 1 - Related articles

IL-7 Knocks the Socs Off Chronic Viral Infection

[PDF] from citninfo.comIA Parish… - Cell, 2011 - Elsevier
... To test this hypothesis, they administer IL-7 to mice infected with lymphocytic
choriomeningitis virus (LCMV) clone 13, a powerful animal model of chronic viral infection
that recapitulates many aspects of persistent virus infection in humans. ...
All 5 versions

Migration of cytotoxic lymphocytes in cell cycle permits local MHC I–dependent control of division at sites of viral infection

[PDF] from nyu.eduSS Kang, J Herz, JV Kim, D Nayak… - The Journal of …, 2011 - jem.rupress.org
... Migration of cytotoxic lymphocytes in cell cycle permits local MHC I–dependent control of division
at sites of viral infection. ... However, it is presently not known whether this division program proceeds
during migration or is influenced locally at sites of viral infection. ...
Related articles - All 4 versions

Immunotherapy for persistent viral infections and associated disease

SH van der Burg, R Arens… - Trends in immunology, 2011 - Elsevier
... should target these features of the failing immune system to enhance the quantity and quality
of the virus-specific T cell response (Figure 1). These features are shared with chronic lymphocytic
choriomeningitis virus (LCMV), and other viral persistent infection models in mice. ...
Related articles - All 3 versions

Chronic fatigue syndrome, the immune system and viral infection

AS Bansal, AS Bradley, KN Bishop, S Kiani… - Brain, Behavior, and …, 2011 - Elsevier
... onset persistent tiredness for over six months. In 1988 Holmes et al. from the US Centre for
Disease Control (CDC) drafted the working case definition for CFS to help standardise the patient
population for research purposes and to avoid the connection with viral infection after ...

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