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Signal integration by DegS and RseB governs the σE-mediated envelope stress response in Escherichia coli

[HTML] from pnas.orgR Chaba, BM Alba, MS Guo… - Proceedings of the …, 2011 - National Acad Sciences
In Escherichia coli, the σ E transcription factor monitors and maintains outer membrane (OM)
integrity by activating genes required for assembly of its two key components, outer membrane
proteins (OMPs) and lipopolysaccharide (LPS) and by transcribing small RNAs to down- ...
Cited by 1 - Related articles - All 4 versions

A tyrosine-sulfated CCR5-mimetic peptide promotes conformational transitions in the HIV-1 envelope glycoprotein

JA Kwong, T Dorfman, BD Quinlan… - Journal of …, 2011 - Am Soc Microbiol
The HIV-1 envelope glycoprotein is a trimeric complex of heterodimers composed of a surface
glycoprotein, gp120, and a transmembrane component, gp41. The association of this complex
with CD4 stabilizes the coreceptor-binding site of gp120 and promotes the exposure of ...
Related articles - All 4 versions

Insights into the mechanism of HIV-1 envelope induced membrane fusion as revealed by its inhibitory peptides

A Ashkenazi… - European Biophysics Journal, 2011 - Springer
Abstract HIV-1 fusion with its target cells is mediated by the glycoprotein 41 (gp41)
transmembrane subunit of the viral envelope glycoprotein (ENV). The current models
propose that gp41 undergoes several conformational changes between the apposing viral ...
Cited by 1 - Related articles - All 3 versions

Repo-Man Coordinates Chromosomal Reorganization with Nuclear Envelope Reassembly during Mitotic Exit

P Vagnarelli, S Ribeiro, L Sennels… - Developmental Cell, 2011 - Elsevier
Repo-Man targets protein phosphatase 1 γ (PP1γ) to chromatin at anaphase onset and
regulates chromosome structure during mitotic exit. Here, we show that a Repo-Man: PP1
complex forms in anaphase following dephosphorylation of Repo-Man. Upon activation, ...
Cited by 1

Clinical evaluation of a soluble trimeric HIV-1 envelope glycoprotein vaccine

RW Sanders - Expert Review of Vaccines, 2011 - ingentaconnect.com
The recent RV144 trial in Thailand yielded a 31% efficacy and showed for the first time that vaccine
protection against HIV can be achieved [1]. However, the results also clearly indicated that vaccine
design needs to improve. The vaccine regimen tested in the RV144 trial consisted of a ...

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