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Nifedipine treatment reduces brain damage after transient focal ischemia, possibly through its antioxidative effects

M Yamato, T Shiba, T Ide, Y Honda… - Hypertension …, 2011 - nature.com
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Effect of nifedipine on anorectal sensorimotor functions in health and fecal incontinence

AE Bharucha, J Edge… - American Journal of …, 2011 - Am Physiological Soc
The mechanisms of increased rectal stiffness in women with fecal incontinence (FI) and rectal
urgency are not understood. Our hypothesis was that distention-induced activation of mechanosensitive
L-type calcium channels in smooth muscle contributes to increased rectal stiffness in FI. ...
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Long-term treatment with nifedipine suppresses coronary hyperconstricting responses and inflammatory changes induced by paclitaxel-eluting stent in pigs in vivo: …

R Tsuburaya, S Yasuda, T Shiroto… - European Heart …, 2011 - Eur Soc Cardiology
Methods and results Paclitaxel-eluting stent (PES) and a BMS were randomly implanted in the
left coronary arteries in male domestic pigs with and without long-acting nifedipine (NIF, 4
mg/kg/day) for 4 weeks (n = 7 each). Coronary vasomotion was evaluated by quantitative ...
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CYP3As catalyze nifedipine oxidation in pig liver microsomes: Enzyme kinetics, inhibition and functional expression

J Jiang, J Wang, H Cai, K Li… - Catalysis Communications, 2011 - Elsevier
Cytochrome P450 (CYP) 3As have received much attention because of their importance in drug
metabolism. However, information on CYP3As in pigs is still largely incomplete. Herein, we focused
on the involvement of CYP3As in nifedipine oxidation in pig liver microsomes. Enzyme ...
Cited by 1 - Related articles

Nifedipine Affects the Course of Salmonella enterica Serovar Typhimurium Infection by Modulating Macrophage Iron Homeostasis

SM Mair, M Nairz, R Bellmann-Weiler… - Journal of Infectious …, 2011 - jid.oxfordjournals.org
Results. In RAW264.7 cells, nifedipine treatment significantly reduced intracellular bacterial survival
of Salmonella enterica serovar Typhimurium and Chlamydophila pneumoniae. This could be
attributed to the induction of the iron exporter ferroportin 1, which limited the availability of ...

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