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Phenotypic heterogeneity and instability of human ovarian tumor-initiating cells

[HTML] from nih.govJM Stewart, PA Shaw, C Gedye… - Proceedings of the …, 2011 - National Acad Sciences
The cancer stem cell (CSC) model proposes that tumors have a hierarchical organization in which
only some cells indefinitely self-renew and thereby sustain tumor growth. In addition, the CSC
model requires that tumor-initiating cells (TICs) be prospectively isolatable on the basis of ...
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Tumor-infiltrating Cytotoxic T Lymphocytes as Independent Prognostic Factor in Epithelial Ovarian Cancer With Wilms Tumor Protein 1 Overexpression

R Vermeij, GH de Bock, N Leffers… - Journal of …, 2011 - journals.lww.com
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information, please refer to our Privacy Policy. ... Skip Navigation Links Home > Current ...
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Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease

[HTML] from nih.govTW James, N Frias-Staheli… - Proceedings of the …, 2011 - National Acad Sciences
The attachment of ubiquitin (Ub) and the Ub-like (Ubl) molecule interferon-stimulated gene 15
(ISG15) to cellular proteins mediates important innate antiviral responses. Ovarian tumor
(OTU) domain proteases from nairoviruses and arteriviruses were recently found to ...
Cited by 2 - Related articles - All 5 versions

BORIS/CTCFL-mediated transcriptional regulation of the hTERT telomerase gene in testicular and ovarian tumor cells

[HTML] from nih.govS Renaud, D Loukinov, L Alberti… - Nucleic Acids …, 2011 - Oxford Univ Press
Telomerase activity, not detectable in somatic cells but frequently activated during
carcinogenesis, confers immortality to tumors. Mechanisms governing expression of the catalytic
subunit hTERT, the limiting factor for telomerase activity, still remain unclear. We ...
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MHC Class I–Presented Tumor Antigens Identified in Ovarian Cancer by Immunoproteomic Analysis Are Targets for T-Cell Responses against Breast and Ovarian …

MA Morse, AA Secord, K Blackwell… - Clinical Cancer …, 2011 - AACR
Experimental Design: Mixtures of human leukocyte antigen A2 (HLA-A2)-binding ovarian
cancer-associated peptides were used to activate naive T cells to generate antigen-specific T
cells that could recognize ovarian and breast cancers in vitro. Combinations of these ...
Cited by 1 - Related articles - All 3 versions

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