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R Maehr, EO Mazzoni, DA Melton… - Mechanisms of …, 2011 - Elsevier
Wnt signaling has been implicated in many developmental processes, but its role in early endoderm
development is not well understood. Wnt signaling is active in posterior endoderm as early as
E7.5. Genetic and chemical activation show that the Wnt pathway acts directly on ...
GM Keller… - US Patent 20,110,212,061, 2011 - freepatentsonline.com
The present invention provides cell populations that are enriched for mesendoderm and
mesoderm, and cell populations that are enriched for endoderm. The cell populations of the invention
are useful for generating cells for cell replacement therapy. The present invention further ...
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S Brown, A Teo, S Pauklin, N Hannan… - STEM CELLS, 2011 - Wiley Online Library
Author contributions: SB: Conception and design, Collection and/or assembly of data, Data analysis
and interpretation; AT: Collection and/or assembly of data; SP: Collection and/or assembly of
data; NH: Collection and/or assembly of data; CH-H C.: Collection and/or assembly of ...
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[HTML] from cshlp.orgAKK Teo, SJ Arnold, MWB Trotter… - Genes & …, 2011 - genesdev.cshlp.org
Understanding the molecular mechanisms controlling early cell fate decisions in mammals is
a major objective toward the development of robust methods for the differentiation of human
pluripotent stem cells into clinically relevant cell types. Here, we used human embryonic ...
Cited by 5 - Related articles - All 3 versions
FW Sand, A Hornblad, JK Johansson, C Loren… - Developmental …, 2011 - Elsevier
Endoderm development is dependent on inductive signals from different structures in close
vicinity, including the notochord, lateral plate mesoderm and endothelial cells. Recently, we demonstrated
that a functional vascular system is necessary for proper pancreas development, and that ...
Cited by 1 - Related articles - All 2 versions

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