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Centromere Identity, Function, and Epigenetic Propagation across Cell Divisions.

BE Black, LE Jansen, DR Foltz… - Cold Spring Harbor …, 2011 - ncbi.nlm.nih.gov
The key to understanding centromere identity is likely to lie in the chromatin containing the histone
H3 variant CENP-A. CENP-A is the prime candidate to carry the epigenetic information that specifies
the chromosomal location of the centromere in nearly all eukaryotic species, raising ...
Related articles - All 3 versions

Epigenetic centromere propagation and the nature of CENP-A nucleosomes

BE Black… - Cell, 2011 - Elsevier
Centromeres direct chromosome inheritance, but in multicellular organisms their positions on
chromosomes are primarily specified epigenetically rather than by a DNA sequence. The major
candidate for the epigenetic mark is chromatin assembled with the histone H3 variant ...
Cited by 5 - Related articles - All 4 versions

Cell cycle dynamics of histone variants at the centromere, a model for chromosomal landmarks

E Boyarchuk, R Montes de Oca… - Current Opinion in Cell …, 2011 - Elsevier
Classical heterochromatin chromosomal landmarks, such as centromeres and telomeres, are
characterized by specific chromatin signatures. Among these, the incorporation of histone variants
has recently emerged as an important feature. Using the centromere as a paradigm, we ...
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Structural basis for recognition of centromere histone variant CenH3 by the chaperone Scm3

Z Zhou, H Feng, BR Zhou, R Ghirlando, K Hu… - Nature, 2011 - nature.com
The centromere is a unique chromosomal locus that ensures accurate segregation of chromosomes
during cell division by directing the assembly of a multiprotein complex, the kinetochore 1 . The
centromere is marked by a conserved variant of conventional histone H3 termed CenH3 ...
Cited by 7 - Related articles - All 5 versions

Recognition of the centromere-specific histone Cse4 by the chaperone Scm3

[HTML] from nih.govUS Cho… - Proceedings of the National …, 2011 - National Acad Sciences
A specialized nucleosome is a component of all eukaryotic kinetochores. The core of this nucleosome
contains a centromere-specific histone, CENP-A (the Cse4 gene product in budding yeast), instead
of the usual H3. Assembly of a centromeric nucleosome depends on a specific ...
Cited by 2 - Related articles - All 4 versions

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