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Structure and function of an irreversible agonist-[bgr] 2 adrenoceptor complex

DM Rosenbaum, C Zhang, JA Lyons, R Holl… - Nature, 2011 - nature.com
G-protein-coupled receptors (GPCRs) are eukaryotic integral membrane proteins that modulate
biological function by initiating cellular signalling in response to chemically diverse agonists.
Despite recent progress in the structural biology of GPCRs 1 , the molecular basis for ...
Cited by 33 - Related articles - All 6 versions

Charge Separation is Virtually Irreversible in Photosystem II Core Complexes with Oxidized Primary Quinone Acceptor

CD van der Weij− de Wit, JP Dekker… - The Journal of …, 2011 - ACS Publications
X-ray structures of the Photosystem II (PSII) core revealed relatively large interpigment distances
between the CP43 and CP47 antenna complexes and the reaction center (RC) with respect to
the interpigment distances in a single unit. This finding questions the possibility of fast ...
Cited by 1 - Related articles - All 3 versions

TNF/IL‐17 interplay induces S100A8, IL‐1β, and MMPs, and drives irreversible cartilage destruction In Vivo: Rationale for combination treatment during arthritis

MI Koenders, RJ Marijnissen, I Devesa… - Arthritis & …, 2011 - Wiley Online Library
Page 1. TNF / IL-17 Interplay Induces S100A8, IL-1β, and MMPs, and Drives Irreversible Cartilage
Destruction In Vivo: Rationale for Combination Treatment During Arthritis. ... irreversible cartilage
destruction was not merely the result of enhanced inflammation, but a ...
Related articles - All 2 versions

Advances pertaining to the pharmacology and interactions of irreversible nonselective monoamine oxidase inhibitors

PK Gillman - Journal of clinical psychopharmacology, 2011 - journals.lww.com
Recent advances clarifying the pharmacology and interactions of irreversible nonselective monoamine
oxidase inhibitors that have not been considered in depth lately are discussed. These new data
elucidate aspects of enzyme inhibition and pharmacokinetic interactions involving amine ...
Cited by 1 - Related articles - All 4 versions

Salmonella enterica serovar Typhimurium binds to HeLa cells via Fim-mediated reversible adhesion and irreversible type three secretion system 1-mediated docking

B Misselwitz, SK Kreibich, S Rout… - Infection and …, 2011 - Am Soc Microbiol
The food-borne pathogen Salmonella enterica serovar Typhimurium invades mammalian epithelial
cells. This multistep process comprises bacterial binding to the host cell, activation of the Salmonella
type three secretion system 1 (T1), injection of effector proteins, triggering of host cell ...
Cited by 5 - Related articles - All 2 versions

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