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The Sirtuin 2 microtubule deacetylase is an abundant neuronal protein that accumulates in the aging CNS

MM Maxwell, EM Tomkinson, J Nobles… - Human Molecular …, 2011 - Oxford Univ Press
Sirtuin 2 (SIRT2) is one of seven known mammalian protein deacetylases homologous to the
yeast master lifespan regulator Sir2. In recent years, the sirtuin protein deacetylases have emerged
as candidate therapeutic targets for many human diseases, including metabolic and age- ...

Abundant ammonia in primitive asteroids and the case for a possible exobiology

[PDF] from stanford.eduS Pizzarello, LB Williams, J Lehman… - Proceedings of the …, 2011 - National Acad Sciences
Carbonaceous chondrites are asteroidal meteorites that contain abundant organic materials.
Given that meteorites and comets have reached the Earth since it formed, it has been proposed
that the exogenous influx from these bodies provided the organic inventories necessary ...
Cited by 3 - Related articles - All 6 versions

An abundant, truncated human sulfonylurea receptor 1 splice variant has prodiabetic properties and impairs sulfonylurea action

D Schmid, M Stolzlechner, A Sorgner… - Cellular and Molecular …, 2011 - Springer
Abstract An alternatively spliced form of human sulfo- nylurea receptor (SUR) 1 mRNA lacking
exon 2 (SUR1D2) has been identified. The omission of exon 2 caused a frame shift and an immediate
stop codon in exon 3 leading to translation of a 5.6-kDa peptide that comprises the N-ter- ...
Related articles - All 2 versions

Abundant class of non-coding RNA regulates development in the social amoeba dictyostelium discoideum

L Avesson, HT Schumacher, P Fechter… - RNA …, 2011 - es.landesbioscience.com
Non-coding (nc)RNAs are important players in most biological processes. Although small RNAs
such as microRNAs and small interfering RNAs have emerged as exceptionally important regulators
of gene expression, great numbers of larger ncRNAs have also been identified. Many of ...
Cited by 1 - Cached

Extracellular DNA is abundant and important for microcolony strength in mixed microbial biofilms

DM Dominiak, JL Nielsen… - Environmental …, 2011 - Wiley Online Library
A new approach for quantification of extracellular DNA (eDNA) in mixed biofilms at microscale
resolu- tion was developed and combined with other staining techniques to assess the
origin, abundance and role of eDNA in activated sludge biofilms. Most eDNA was found ...
Cited by 5 - Related articles - All 3 versions

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