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[PDF] from uccs.eduA Cerutti - Annual Review of Immunology, 2011 - annualreviews.org
Mucosal surfaces are colonized by large communities of commensal bacteria and represent
the primary site of entry for pathogenic agents. To prevent microbial intrusion, mucosal B cells
release large amounts of immunoglobulin (Ig) molecules through multiple follicular and ...
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S Pruzina, GT Williams, G Kaneva… - Protein Engineering …, 2011 - Oxford Univ Press
Mice carrying human immunoglobulin transloci were immunised with HIV-1 gp140 antigen to
gain insight into the range and nature of human monoclonal antibodies (mAbs) that can be elicited
from such humanised mice. Using five-feature mice that harbour YAC-based germline- ...
A Plückthun, A Honegger… - US Patent …, 2011 - freepatentsonline.com
22. A nucleic acid molecule encoding a stabilized chimeric immunoglobulin or immunoglobulin
fragment (chimera) that comprises i) VH domain antigen-binding loops from a donor immunoglobulin
or immunoglobulin fragment (donor) which is able to bind to an antigen, and ii) VH ...
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X Ren, R Siegel, U Kim… - Molecular Cell, 2011 - Elsevier
B cell-specific coactivator OCA-B, together with Oct-1/2, binds to octamer sites in promoters and
enhancers to activate transcription of immunoglobulin (Ig) genes, although the mechanisms underlying
their roles in enhancer-promoter communication are unknown. Here, we demonstrate a ...
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Y He… - … of the National Academy of Sciences, 2011 - National Acad Sciences
Edited by Jeffrey V. Ravetch, The Rockefeller University, New York, NY, and approved June
20, 2011 (received for review May 2, 2011) Fc receptors transport maternal antibodies across
epithelial cell barriers to passively immunize newborns. FcRY, the functional counterpart ...

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