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[HTML] A Helminth Immunomodulator Exploits Host Signaling Events to Regulate Cytokine Production in Macrophages

[HTML] from plos.orgC Klotz, T Ziegler, AS Figueiredo, S Rausch… - PLoS Pathogens, 2011 - dx.plos.org
Helminths have the ability to interfere with their host's immune response, thus downregulating
inflammatory responses. We previously demonstrated the role of helminth infections or isolated
helminth proteins in suppressing bystander immune responses in mouse models of ...
Cited by 2 - Related articles - Cached - All 5 versions

Cryptococcus neoformans galactoxylomannan is a potent negative immunomodulator, inspiring new approaches in anti-inflammatory immunotherapy

A Vecchiarelli, E Pericolini, E Gabrielli… - …, 2011 - Future Medicine
Cryptococcus neoformans is an opportunistic fungal pathogen responsible for life-threatening
infections in immunocompromised individuals and occasionally in those with no known immune
impairment. The fungus is endowed with several virulence factors, including capsular ...

Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases

V Chi, MW Pennington, RS Norton, E Tarcha… - Toxicon, 2011 - Elsevier
Electrophysiological and pharmacological studies coupled with molecular identification have
revealed a unique network of ion channels—Kv1.3, KCa3.1, CRAC (Orai1 + Stim1), TRPM7,
Cl swell —in lymphocytes that initiates and maintains the calcium signaling cascade ...

IMMUNOMODULATOR PARTICLES AND METHODS OF TREATING

B Hubby, A Murphy, J Kindig… - US Patent …, 2011 - freepatentsonline.com
A method of stimulating an immune response in a subject including administering a
micrometer-sized particle coupled with an antigen to the subject, wherein increasing the aspect
ratio of the micrometer-sized particle increases the immune response. A method of ...
Cached

The plant-based immunomodulator curcumin as a potential candidate for the development of an adjunctive therapy for cerebral malaria

[HTML] from malariajournal.comP Mimche, D Taramelli… - Malaria Journal, 2011 - malariajournal.com
The clinical manifestations of cerebral malaria (CM) are well correlated with underlying major
pathophysiological events occurring during an acute malaria infection, the most important of
which, is the adherence of parasitized erythrocytes to endothelial cells ultimately leading ...
Cited by 1 - Related articles - Cached - All 8 versions

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