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Inhibition of Alanine Aminotransferase in Silico and in Vivo Promotes Mitochondrial Metabolism to Impair Malignant Growth

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Check for Full TextG Beuster, K Zarse, C Kaleta, R Thierbach… - Journal of Biological …, 2011 - ASBMB
Cancer cells commonly exhibit increased nonoxidative d-glucose metabolism whereas induction
of mitochondrial metabolism may impair malignant growth. We have first used an in silico method
called elementary mode analysis to identify inhibition of ALAT (l-alanine ...
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Relationships between alanine aminotransferase levels, abnormal liver echogenicity, and metabolic syndrome

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Check for Full TextCH Hsu, JY Wang, YL Chen… - The Journal of the …, 2011 - Am Board Family Med
Methods: Data from 3065 men aged 65 years or older who were undergoing a routine health
examination and who were not taking any medications for MetS were analyzed
retrospectively. The patients were divided into 4 groups: group N (n = 1228; patients have ...
Cited by 2 - Related articles - All 5 versions

Molecular Beacon Based Bioassay for Highly Sensitive and Selective Detection of Nicotinamide Adenine Dinucleotide and the Activity of Alanine Aminotransferase

Check for Full TextZ Tang, P Liu, C Ma, X Yang, K Wang… - Analytical …, 2011 - ACS Publications
We have developed a new approach to detect nicotinamide adenine dinucleotide (NAD + ) with
high specificity and sensitivity using molecular beacons (MBs) and employed it in the investigation
of NAD + related biological processes, such as calorie restriction and alanine ...
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Predictive Effect of Serial Serum Alanine Aminotransferase Levels on Spontaneous HBeAg Seroconversion in Chronic Genotypes B and C HBV infected Children

Check for Full TextJF Wu, YR Su, CH Chen, HL Chen… - Journal of Pediatric …, 2011 - journals.lww.com
Methods: One hundred and four HBeAg-positive chronic genotype B or C HBV infected patients
were included into this long-term prospective cohort study (mean initial age, 7.20 years). Serial
serum ALT levels and HBV serology markers were measured every 6-12 months. The ...
All 3 versions

… liver hyperintensity in malignant biliary obstruction on diffusion weighted MR imaging: associated MRI findings and relationship with serum alanine aminotransferase …

HH Tam, DJ Collins, T Wallace… - British Journal of …, 2011 - Br Inst Radiology
ABSTRACT. Objective: Segmental liver hyperintensity can be observed in malignant biliary obstruction
on diffusion weighted MRI (DW-MRI). We describe MRI findings associated with this sign and
evaluate whether DW-MRI segmental hyperintensity has any relationship with serum ...
Related articles - Check for Full Text - All 3 versions

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